Prosthetic joint infections: diagnosis, management, and complications of the two-stage replacement arthroplasty

J Porrino, A Wang, A Moats, H Mulcahy, K Kani - Skeletal radiology, 2020 - Springer
Despite improved strategies to prevent prosthetic joint infection, as the total number of joint
replacements increases, so does the absolute number of infections. Radiography serves as …

Periprosthetic joint infection and the trojan horse theory: examining the role of gut dysbiosis and epithelial integrity

E Chisari, J Cho, M Wouthuyzen-Bakker… - The Journal of …, 2022 - Elsevier
Background Periprosthetic joint infection (PJI) is an uncommon yet dreadful complication
after total joint arthroplasty. Emerging evidence suggested a role for the gut microbiome in …

Definition of successful infection management and guidelines for reporting of outcomes after surgical treatment of periprosthetic joint infection: from the workgroup of …

YA Fillingham, CJ Della Valle, LI Suleiman… - JBJS, 2019 - journals.lww.com
The Musculoskeletal Infection Society (MSIS) definition for periprosthetic joint infection (PJI)
has helped to standardize PJI research by providing a consistent population among …

Sialic acid conjugate-modified liposomes enable tumor homing of epirubicin via neutrophil/monocyte infiltration for tumor therapy

J Ding, D Sui, M Liu, Y Su, Y Wang, M Liu, X Luo, X Liu… - Acta Biomaterialia, 2021 - Elsevier
Neutrophils and monocytes (N/Ms) are potential candidates for the delivery of therapeutic
agents to the tumor microenvironment (TME) because of their tumor-accumulating nature. L …

Next-generation sequencing not superior to culture in periprosthetic joint infection diagnosis

BJ Kildow, SP Ryan, R Danilkowicz… - The bone & joint …, 2021 - boneandjoint.org.uk
Aims Use of molecular sequencing methods in periprosthetic joint infection (PJI) diagnosis
and organism identification have gained popularity. Next-generation sequencing (NGS) is a …

Diagnostic utility of a novel point-of-care test of calprotectin for periprosthetic joint infection after total knee arthroplasty: a prospective cohort study

J Warren, HK Anis, K Bowers, T Pannu, J Villa, AK Klika… - JBJS, 2021 - journals.lww.com
Background: Despite several synovial fluid biomarkers for the diagnosis of periprosthetic
joint infection (PJI) having been investigated, point-of-care (POC) tests using these …

The value of calprotectin in synovial fluid for the diagnosis of chronic prosthetic joint infection

Z Zhang, Y Cai, G Bai, C Zhang, W Li… - Bone & joint …, 2020 - boneandjoint.org.uk
Aims This study aimed to evaluate calprotectin in synovial fluid for diagnosing chronic
prosthetic joint infection (PJI). Methods A total of 63 patients who were suspected of PJI were …

Intestinal methicillin-resistant Staphylococcus aureus causes prosthetic infection via 'Trojan Horse'mechanism: evidence from a rat model

H Zhu, H Jin, C Zhang, T Yuan - Bone & Joint Research, 2020 - boneandjoint.org.uk
Aims Methicillin-resistant Staphylococcus aureus (MRSA) can cause wound infections via a
'Trojan Horse'mechanism, in which neutrophils engulf intestinal MRSA and travel to the …

Diagnosis and management of periprosthetic joint infection after shoulder arthroplasty

ME Cooper, NN Trivedi, L Sivasundaram… - JBJS …, 2019 - journals.lww.com
Diagnosis and Management of Periprosthetic Joint Infection A... : JBJS Reviews Diagnosis
and Management of Periprosthetic Joint Infection After Shoulder Arthroplasty : JBJS Reviews …

Impact of positive cultures during the second stage of a two-stage exchange: systematic review and meta-analysis

M Sabater-Martos, L Boadas, R Trebše… - The Journal of …, 2024 - Elsevier
Background Two-stage exchange is a frequently performed procedure in patients who have
a periprosthetic joint infection. Positive cultures when performing the second stage are …