Heme homeostasis and its regulation by hemoproteins in bacteria

Y Li, S Han, H Gao - mLife, 2024 - Wiley Online Library
Heme is an important cofactor and a regulatory molecule involved in various physiological
processes in virtually all living cellular organisms, and it can also serve as the primary iron …

[HTML][HTML] Metabolic Engineering of Escherichia coli for Production of a Bioactive Metabolite of Bilirubin

H Chen, P Xiong, N Guo, Z Liu - International Journal of Molecular …, 2024 - mdpi.com
Bilirubin (BR) is an important ingredient of a valuable Chinese medicine, Calculus bovis.
Over recent decades, increasing evidence has confirmed that BR offers health benefits in …

Accelerated 5-aminolevulinic acid biosynthesis by coupling aconitase and ALA synthase in engineered Escherichia coli

PH Lai, IS Ng - Biochemical Engineering Journal, 2024 - Elsevier
In recent years, 5-aminolevulinic acid (5-ALA) has attracted significant interest due to its
roles as a photodynamic prodrug and an antiviral agent. In this study, we present a new …

Creation of Heme and Hemoglobin Producers Based on Microorganisms

OH Pidkurhanna, LB Zelena, SM Shulha - Cytology and Genetics, 2024 - Springer
At present, the production of hemoglobin using microorganisms is an actual and urgent
problem for solving the needs of medicine and the food industry. Its microbiological …

Engineering Coupled Consortia-Based Biosensors using Incoherent Feedforward Loops

R Daniel, R Huang, V Kravchik, N Geva-Zatorsky - 2024 - researchsquare.com
Synthetic multicellular systems offer the potential for performing complex biological tasks
through coordinated cell-to-cell communication. However, the engineering of these systems …