DNA methylation is an important epigenetic mechanism that regulates gene expression. To
date, most DNA methylation studies have focussed on CpG islands in the gene promoter …

Cells experience both endogenous and exogenous DNA damage daily. To maintain
genome integrity and suppress tumorigenesis, individuals have evolutionarily acquired a …

Objective: To evaluate whether neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte
ratio (PLR), lymphocyte to monocyte ratio (LMR) and monocyte-to-white blood cell ratio …

Some lncRNAs can encode small nucleolar RNAs (snoRNAs), called small nucleolar RNA
host genes (SNHGs), which have exerted certain predictive values for the prognosis of some …

Colorectal cancer (CRC) is the third most common malignant tumor. DNA damage plays a
crucial role in tumorigenesis, and abnormal DNA repair pathways affect the occurrence and …

Risk stratification using prognostic markers facilitates clinical decision-making in treatment of
osteosarcoma (OS). In this study, we performed a comprehensive analysis of DNA …

Aim: The authors investigated the clinical role of MTFR2 in hepatocellular carcinoma (HCC)
progression. Results: MTFR2 expression and methylation were abnormal in HCC tissues …

RNA epigenetics is perhaps the most recent field of interest for translational epigeneticists.
RNA modifications create such an extensive network of epigenetically driven combinations …

Of the different types of lung cancer, lung squamous cell cancer (LUSC) has the second
highest rates of morbidity and mortality, which have been increasing in recent years …

The DNA damage response (DDR) is an essential mechanism for maintaining genomic
stability. Although DDR-targeted therapeutic strategies are being developed in several …