Peptide-based coacervates in therapeutic applications
L Ma, X Fang, C Wang - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Coacervates are droplets formed by liquid‒liquid phase separation. An increasing number
of studies have reported that coacervates play an important role in living cells, such as in the …
of studies have reported that coacervates play an important role in living cells, such as in the …
Rational design of elastin-like polypeptide fusion proteins to tune self-assembly and properties of protein vesicles
Y Li, DR Dautel, MA Gray, ME McKenna… - Journal of Materials …, 2023 - pubs.rsc.org
Protein vesicles made from bioactive proteins have potential value in drug delivery,
biocatalysis, and as artificial cells. As the proteins are produced recombinantly, the ability to …
biocatalysis, and as artificial cells. As the proteins are produced recombinantly, the ability to …
Application of thermoresponsive intrinsically disordered protein polymers in nanostructured and microstructured materials
Modulation of inter‐and intramolecular interactions between bioinspired designer molecules
can be harnessed for developing functional structures that mimic the complex hierarchical …
can be harnessed for developing functional structures that mimic the complex hierarchical …
Controlled delivery of vancomycin from collagen-tethered peptide vehicles for the treatment of wound infections
Despite the great promise of antibiotic therapy in wound infections, antibiotic resistance
stemming from frequent dosing diminishes drug efficacy and contributes to recurrent …
stemming from frequent dosing diminishes drug efficacy and contributes to recurrent …
A Library of Elastin-like Proteins with Tunable Matrix Ligands for In Vitro 3D Neural Cell Culture
RA Suhar, MS Huang, RS Navarro… - …, 2023 - ACS Publications
Hydrogels with encapsulated cells have widespread biomedical applications, both as tissue-
mimetic 3D cultures in vitro and as tissue-engineered therapies in vivo. Within these …
mimetic 3D cultures in vitro and as tissue-engineered therapies in vivo. Within these …
Investigating the Hydrogen Bond-Induced Self-Assembly of Polysulfamides Using Molecular Simulations and Experiments
In this paper, we present a synergistic, experimental, and computational study of the self-
assembly of N, N′-disubstituted polysulfamides driven by hydrogen bonds (H-bonds) …
assembly of N, N′-disubstituted polysulfamides driven by hydrogen bonds (H-bonds) …
Laccase-mediated formation of hydrogels based on silk-elastin-like protein polymers with ultra-high molecular weight
S Wang, W Huang, Z Feng, X Tian, D Wang… - International Journal of …, 2023 - Elsevier
As artificial extracellular matrix-like materials, silk-elastin-like protein (SELP) hydrogels, with
excellent mechanical properties, high tunability, favorable biocompatibility, and controlled …
excellent mechanical properties, high tunability, favorable biocompatibility, and controlled …
Controlled Release of Drugs from Extracellular Matrix-Derived Peptide-Based Nanovesicles through Tailored Noncovalent Interactions
Elastin–collagen nanovesicles (ECnV) have emerged as a promising platform for drug
delivery due to their tunable physicochemical properties and biocompatibility. The potential …
delivery due to their tunable physicochemical properties and biocompatibility. The potential …
Molecular modeling and simulation of polymer nanocomposites with nanorod fillers
We present a coarse-grained (CG) molecular dynamics (MD) simulation study of polymer
nanocomposites (PNCs) containing nanorods with homogeneous and patchy surface …
nanocomposites (PNCs) containing nanorods with homogeneous and patchy surface …
Flexible customization of the self‐assembling abilities of short elastin‐like peptide Fn analogs by substituting N‐terminal amino acids
K Suyama, M Shimizu, I Maeda, T Nose - Biopolymers, 2022 - Wiley Online Library
Elastin‐like peptides (ELPs) are thermoresponsive biopolymers inspired by the
characteristic repetitive sequences of natural elastin. As ELPs exhibit temperature …
characteristic repetitive sequences of natural elastin. As ELPs exhibit temperature …