Gelsolin (GSN), one of the most abundant actin-binding proteins, is involved in cell motility,
shape and metabolism. As a member of the GSN superfamily, GSN is a highly structured …

The NME (Non-metastatic) family members, also known as NDPKs (nucleoside diphosphate
kinases), were originally identified and studied for their nucleoside diphosphate kinase …

Nucleoside diphosphate kinases (NDPK) are nucleotide metabolism enzymes encoded by
NME genes (also called NM23). Given the fact that not all NME-encoded proteins are …

NM23 (NME) is a metastasis suppressor that significantly reduces metastasis without
affecting primary tumor size, however, the precise molecular mechanisms are not completely …

In estrogen receptor‐negative breast cancer patients, metastatic relapse usually occurs in
the lung and is responsible for the fatal outcome of the disease. Thus, a better …

Glucose is the principal cellular energy source in humans and maintenance of glucose
homeostasis is critical for survival. Glucose uptake into peripheral skeletal muscle and …

Nucleoside triphosphate (NTP) s, like ATP (adenosine 5'-triphosphate) and GTP (guanosine
5'-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel …

Metastasis is one of the major obstacles for the successful therapy of breast cancer. To
inhibit the metastasis and growth of breast cancer simultaneously, a new docetaxel (DTX) …

MRE11, the core of the MRE11/RAD50/NBS1 complex, is one of key DNA damage response
proteins. Increasing evidence suggests that its expression in cancer cells is critical to …

The present study aimed to identify molecules associated with lymphovascular invasion
(LVI) and perineural invasion (PNI) and to examine their biological behavior in colorectal …