Fungal-bacterial interactions in health and disease

W Krüger, S Vielreicher, M Kapitan, ID Jacobsen… - Pathogens, 2019 - mdpi.com
Fungi and bacteria encounter each other in various niches of the human body. There, they
interact directly with one another or indirectly via the host response. In both cases …

The Virtuous Galleria mellonella Model for Scientific Experimentation

I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Enhancing chemical and biological diversity by co-cultivation

DM Selegato, I Castro-Gamboa - Frontiers in microbiology, 2023 - frontiersin.org
In natural product research, microbial metabolites have tremendous potential to provide new
therapeutic agents since extremely diverse chemical structures can be found in the nearly …

Chemical mediators at the bacterial-fungal interface

K Scherlach, C Hertweck - Annual Review of Microbiology, 2020 - annualreviews.org
Interactions among microbes are key drivers of evolutionary progress and constantly shape
ecological niches. Microorganisms rely on chemical communication to interact with each …

Chemical signals driving bacterial–fungal interactions

S Khalid, NP Keller - Environmental Microbiology, 2021 - Wiley Online Library
Microorganisms reside in diverse environmental communities where interactions become
indispensable due to close physical associations. These interactions are driven by chemical …

Risk factors for respiratory Aspergillus fumigatus in German Cystic Fibrosis patients and impact on lung function

U Düesberg, J Wosniok, L Naehrlich, P Eschenhagen… - Scientific reports, 2020 - nature.com
Airway inflammation and chronic lung infections in cystic fibrosis (CF) patients are mostly
caused by bacteria, eg Pseudomonas aeruginosa (PA). The role of fungi in the CF lung is …

Galleria mellonella Larvae as a Model for Investigating Fungal—Host Interactions

A Curtis, U Binder, K Kavanagh - Frontiers in Fungal Biology, 2022 - frontiersin.org
Galleria mellonella larvae have become a widely accepted and utilised infection model due
to the functional homology displayed between their immune response to infection and that …

Polymicrobial Interactions in the Cystic Fibrosis Airway Microbiome Impact the Antimicrobial Susceptibility of Pseudomonas aeruginosa

E Reece, PHA Bettio, J Renwick - Antibiotics, 2021 - mdpi.com
Pseudomonas aeruginosa is one of the most dominant pathogens in cystic fibrosis (CF)
airway disease and contributes to significant inflammation, airway damage, and poorer …

Microbiology's next top model: Galleria in the molecular age

H Dinh, L Semenec, SS Kumar, FL Short… - Pathogens and …, 2021 - academic.oup.com
Galleria mellonella has risen to fame as an invertebrate model organism given its ethical
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …

Let's get physical: bacterial-fungal interactions and their consequences in agriculture and health

BN Steffan, N Venkatesh, NP Keller - Journal of Fungi, 2020 - mdpi.com
Fungi serve as a biological scaffold for bacterial attachment. In some specialized
interactions, the bacteria will invade the fungal host, which in turn provides protection and …