Nitrogen containing heterocycles as anticancer agents: a medicinal chemistry perspective
Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …
drugs are available on the market but they either lack specificity or have poor safety, severe …
Structure activity relationship (SAR) study of benzimidazole scaffold for different biological activities: A mini-review
G Yadav, S Ganguly - European journal of medicinal chemistry, 2015 - Elsevier
Benzimidazoles are the fused heterocyclic ring systems which form an integral part of
vitamin B 12 and have been luring many researchers all over the world to assess their …
vitamin B 12 and have been luring many researchers all over the world to assess their …
Benzimidazole scaffold as anticancer agent: synthetic approaches and structure–activity relationship
Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …
cell growth having the potential to invade or spread to other parts of the body …
Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents
Two new series of benzimidazole bearing oxadiazole [1-(1H-benzo [d] imidazol-2-yl)-3-(5-
substituted-1, 3, 4-oxadiazol-2-yl) propan-1-ones (4a–l)] and triazolo-thiadiazoles [1-(1H …
substituted-1, 3, 4-oxadiazol-2-yl) propan-1-ones (4a–l)] and triazolo-thiadiazoles [1-(1H …
Perspectives of benzimidazole derivatives as anticancer agents in the new era
S Yadav, B Narasimhan - Anti-Cancer Agents in Medicinal …, 2016 - ingentaconnect.com
Cancer is one of the deadliest diseases nowadays and is a great topic for research as the
challenging task is to develop new entities with selectivity towards cancerous cells …
challenging task is to develop new entities with selectivity towards cancerous cells …
Synthetic and naturally occurring heterocyclic anticancer compounds with multiple biological targets
Cancer is a complex group of diseases initiated by abnormal cell division with the potential
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …
Discovery and optimization of novel pyrazole-benzimidazole CPL304110, as a potent and selective inhibitor of fibroblast growth factor receptors FGFR (1–3)
A Yamani, D Zdżalik-Bielecka, J Lipner… - European Journal of …, 2021 - Elsevier
The FGFR family is characterized by four receptors (FGFR 1–4), binding to 18 ligands called
fibroblast growth factors (FGFs). Aberrant activation of FGFs and their FGFRs has been …
fibroblast growth factors (FGFs). Aberrant activation of FGFs and their FGFRs has been …
Synthesis and medicinal applications of benzimidazoles: An overview
S Rajasekhar, B Maiti, M M. Balamurali… - Current Organic …, 2017 - benthamdirect.com
Benzimidazole and its derivatives are regarded as an important heterocyclic motif that
exhibits a wide range of pharmaceutical applications including anticancers …
exhibits a wide range of pharmaceutical applications including anticancers …
Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole-1, 3, 4-oxadiazole derivatives as human topoisomerase types I poison
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for
their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549 …
their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549 …
New pyrazolo-benzimidazole Mannich bases with antimicrobial and antibiofilm activities
C Zalaru, F Dumitrascu, C Draghici, I Tarcomnicu… - Antibiotics, 2022 - mdpi.com
A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized,
characterized by 1H-NMR, 13C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro …
characterized by 1H-NMR, 13C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro …