[HTML][HTML] COVID-19 annual update: a narrative review
M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
[HTML][HTML] SARS-CoV-2: an update on the biological interplay with the human host
Coronavirus Disease 2019 (COVID-19) is an infectious respiratory illness caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease, first identified in the …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease, first identified in the …
[HTML][HTML] Estimating the heritability of SARS-CoV-2 susceptibility and COVID-19 severity
KLR Brown, V Ramlall, M Zietz, U Gisladottir… - Nature …, 2024 - nature.com
SARS-CoV-2 has infected over 340 million people, prompting therapeutic research. While
genetic studies can highlight potential drug targets, understanding the heritability of SARS …
genetic studies can highlight potential drug targets, understanding the heritability of SARS …
[HTML][HTML] Three-year outcomes of post-acute sequelae of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes post-
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …
Environmental variation and genetic diversity contribute to population differences in immune responses to SARS-CoV-2 and COVID-19 risk
M Rotival, L Quintana-Murci - Genes & Immunity, 2023 - nature.com
The COVID-19 pandemic has brought to light considerable clinical variation among
individuals infected with SARS-CoV-2, ranging from asymptomatic cases to fatal outcome …
individuals infected with SARS-CoV-2, ranging from asymptomatic cases to fatal outcome …
[HTML][HTML] Alternative splicing in lung influences COVID-19 severity and respiratory diseases
Alternative splicing generates functional diversity in isoforms, impacting immune response to
infection. Here, we evaluate the causal role of alternative splicing in COVID-19 severity and …
infection. Here, we evaluate the causal role of alternative splicing in COVID-19 severity and …
[HTML][HTML] Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19
High levels of ADAM17 activity have emerged as an important mediator in severe COVID-
19. This study aims to characterize eventual causal relationships between ADAM17 and …
19. This study aims to characterize eventual causal relationships between ADAM17 and …
[HTML][HTML] Molecular Profile of Variants Potentially Associated with Severe Forms of COVID-19 in Amazonian Indigenous Populations
RCC Coelho, CLLP Martins, LF Pastana… - Viruses, 2024 - mdpi.com
Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2. Genome-
wide association studies (GWASs) have suggested a strong association of genetic factors …
wide association studies (GWASs) have suggested a strong association of genetic factors …
[HTML][HTML] Canadian COVID-19 host genetics cohort replicates known severity associations
E Garg, P Arguello-Pascualli, O Vishnyakova… - Plos …, 2024 - journals.plos.org
The HostSeq initiative recruited 10,059 Canadians infected with SARS-CoV-2 between
March 2020 and March 2023, obtained clinical information on their disease experience and …
March 2020 and March 2023, obtained clinical information on their disease experience and …
[HTML][HTML] Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
A Marchal, ET Cirulli, I Neveux, E Bellos… - Human Genetics and …, 2024 - cell.com
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …