Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Cell membranes with their selective permeability play important functions in the tight control
of molecular exchanges between the cytosol and the extracellular environment as the …

With more than ten new FDA approvals since 2001, peptides are emerging as an important
therapeutic alternative to small molecules. However, unlike small molecules, peptides on the …

In the field of nanotherapeutics, gaining cellular entry into the cytoplasm of the target cell
continues to be an ultimate challenge. There are many physicochemical factors such as …

ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

Abstract Cell-penetrating peptides (CPPs), also known as protein transduction domains, are
a class of diverse peptides with 5‑30 amino acids. CPPs are divided into cationic …

Cationic peptides known as protein transduction domains (PTDs) provide a means to deliver
molecules into mammalian cells. Here, nonaarginine (R9), the most efficacious of known …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor resulting in
high rates of morbidity and mortality. A strategy to increase the efficacy of available drugs …

Fluorescent tools have emerged as an important tool for studying the distinct chemical
microenvironments of organelles, due to their high specificity and ability to be used in non …