Background: The global epidemiology of end-stage kidney disease (ESKD) reflects each
nation's unique genetic, environmental, lifestyle, and sociodemographic characteristics. The …

The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

More than 2 million people worldwide are being treated for end-stage kidney disease
(ESKD). This Series paper provides an overview of incidence, modality use (in-centre …

Vascular calcification (VC) is highly prevalent in aging, diabetes mellitus, and chronic kidney
disease (CKD). VC is a strong predictor of cardiovascular morbidity and mortality in the CKD …

The heart and the vascular tree undergo major structural and functional changes when
kidney function declines and renal replacement therapy is required. The many …

Background It is known that sarcopenia is related to malnutrition-inflammation-
atherosclerosis (MIA) syndrome and is an important problem in dialysis patients. The notion …

Ubiquitination and deubiquitination are reversible processes that modify the characteristics
of target proteins, including stability, intracellular localization, and enzymatic activity …

In the last decade, chronic kidney disease (CKD) has been recognized as a major public
health problem globally. CKD is a highly prevalent condition that contributes substantially to …

Dialysis technologies have continued to advance over recent decades; however, these
advancements have not always been met with improved patient outcomes. In part, the high …

Abstract Aims Finerenone (BAY 94-8862) is a novel non-steroidal mineralocorticoid receptor
antagonist. The aim of this study was to compare the efficacy and safety of seven once-daily …