High mobility group box 1 (HMGB1) is a highly conserved, nuclear protein present in all cell
types. It is a multi-facet protein exerting functions both inside and outside of cells …

Pyroptosis is a necrotic form of regulated cell death. Gasdermines (GSDMs) are a family of
intracellular proteins that execute pyroptosis. While GSDMs are expressed as inactive forms …

COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …

Background Spinal cord injury (SCI) favors a persistent pro-inflammatory macrophages/
microglia-mediated response with only a transient appearance of anti-inflammatory …

Among the plethora of debilitating neurological disorders of COVID-19 syndrome in
survivors, the scope of SARS-CoV-2-induced dysautonomia (DNS) is yet to be understood …

Background The 2019 novel coronavirus disease (COVID-19) causes for unresolved
reasons acute respiratory distress syndrome in vulnerable individuals. There is a need to …

The coronavirus disease (COVID-19) pandemic is sweeping the globe. Even with a number
of effective vaccines being approved and available to the public, new cases and escalating …

High mobility group box 1 (HMGB1) is a ubiquitous protein, released passively by necrotic
tissues or secreted actively by stressed cells. Extracellular HMGB1 is a typical damage …

Background Microglial mediated neuroinflammation in the rostral ventrolateral medulla
(RVLM) plays roles in the etiology of stress-induced hypertension (SIH). It was reported that …

Although the innate immune receptor protein, Receptor for Advanced Glycation End
products (RAGE), has been extensively studied, there has been renewed interest in RAGE …