Cholesterol homeostasis is vital for proper cellular and systemic functions. Disturbed
cholesterol balance underlies not only cardiovascular disease but also an increasing …

Phytosterols (PSs), classified into plant sterols and stanols, are bioactive compounds found
in foods of plant origin. PSs have been proposed to exert a wide number of pharmacological …

Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

Dietary plant sterols and stanols as present in our diet and in functional foods are well-
known for their inhibitory effects on intestinal cholesterol absorption, which translates into …

Abstract Cerebrotendinous xanthomatosis (CTX) OMIM# 213700 is a rare autosomal-
recessive lipid storage disease caused by mutations in the CYP27A1 gene; this gene codes …

Sitosterolemia is now considered an extremely rare disorder. Approximately~ 100 patients
have been reported to have sitosterolemia thus far. However, according to The Exome …

Sitosterolemia is an autosomal recessive disorder characterized by increased plant sterol
levels, xanthomas, and accelerated atherosclerosis. Although it was originally reported in …

Significance: Cholesterol is a type of lipid that plays a crucial role in building and
maintaining cell membranes, producing certain hormones, and aiding in digestion. The two …

Whereas LDL-derived cholesterol accumulates in atherosclerotic lesions, HDL particles are
thought to facilitate removal of cholesterol from the lesions back to the liver thereby …

Abstract Purpose of Review The purpose of this review was to summarize important and
updated information on sitosterolemia. Sitosterolemia is an inherited lipid disorder …