Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

The immune system protects the body against harm by inducing inflammation. During the
immune response, cells of the immune system get activated, divided and differentiated in …

Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-stimulated gene that shows
broad antiviral activities against a wide range of enveloped viruses. Here, using an IFN …

Host cells possess the metabolic assets required for viral infection. Recent studies indicate
that control of the host's metabolic resources is a core host–pathogen interaction. Viruses …

The main biological cause of oxysterols is the oxidation of cholesterol. They differ from
cholesterol by the presence of additional polar groups that are typically hydroxyl, keto …

With the frequent outbreaks of emerging infectious diseases in recent years, an effective
broad-spectrum antiviral drug is becoming an urgent need for global public health …

Lipid metabolism reprogramming is an important hallmark of tumor progression. Cancer
cells require high levels of lipid synthesis and uptake not only to support their continued …

In addition to causing cirrhosis and hepatocellular carcinoma, hepatitis C virus (HCV) is
thought to cause hypolipidemia, hepatic steatosis, insulin resistance, metabolic syndrome …

Inflammasomes are multi‐protein complexes that regulate the cleavage of cysteine protease
caspase‐1, secretion of inflammatory cytokines, and induction of inflammatory cell death …

In their seminal papers Hanahan and Weinberg described oncogenic processes a normal
cell undergoes to be transformed into a cancer cell. The functions of ion channels in the …