Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Lithocholic acid (LCA) is a monohydroxy bile acid produced by intestinal flora, which has
been found to be associated with a variety of hepatic and intestinal diseases. LCA is …

Alcoholic liver disease (ALD) is a serious worldwide health problem. Ginsenoside Rc is a
major active ingredient isolated from Panax ginseng, whose pharmacological effects …

Homeothermy is crucial for mammals. Postnatal growth is the key period for young offspring
to acquire gut microbiota. Although gut microbiota may affect mammal thermogenesis, the …

Diabetic cardiomyopathy is characterized by myocardial lipid accumulation and cardiac
dysfunction. Bile acid metabolism is known to play a crucial role in cardiovascular and …

Obesity occurs when overall energy intake surpasses energy expenditure. White adipose
tissue is an energy storage site, whereas brown and beige adipose tissues catabolize stored …

Bile acids are acknowledged as signaling molecules involved in metabolic syndrome. The
Takeda G protein-coupled receptor 5 (TGR5) functions as a significant bile acid receptor …

According to data from the World Health Organization, there were about 3 million deaths
caused by alcohol consumption worldwide in 2016, of which about 50% were related to liver …

Background Alcohol-associated liver disease (ALD) is a worldwide health problem, of which
the effective treatment is still lacking. Both detrimental and protective roles of adipose tissue …

Non-alcoholic fatty liver disease (NAFLD) is one of the major causes of chronic liver injury,
affecting around one-fourth of the general population across the world. Several important …