Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …
[图书][B] Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance
World Health Organization - 2023 - books.google.com
Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …
The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis
Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex …
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex …
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis
S Li, NC Poulton, JS Chang, ZA Azadian… - Nature …, 2022 - nature.com
Mycobacterium tuberculosis (Mtb) infection is notoriously difficult to treat. Treatment efficacy
is limited by Mtb's intrinsic drug resistance, as well as its ability to evolve acquired resistance …
is limited by Mtb's intrinsic drug resistance, as well as its ability to evolve acquired resistance …
Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resistance to bedaquiline, delamanid and pretomanid
PJ Gómez-González, J Perdigao, P Gomes… - Scientific reports, 2021 - nature.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest infectious
diseases worldwide. Multidrug and extensively drug-resistant strains are making disease …
diseases worldwide. Multidrug and extensively drug-resistant strains are making disease …
[HTML][HTML] The evolving biology of Mycobacterium tuberculosis drug resistance
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb) is an ancient disease that has
remained a leading cause of infectious death. Mtb has evolved drug resistance to every …
remained a leading cause of infectious death. Mtb has evolved drug resistance to every …
Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis
Background Bedaquiline is a core drug for the treatment of multidrug-resistant tuberculosis;
however, the understanding of resistance mechanisms is poor, which is hampering rapid …
however, the understanding of resistance mechanisms is poor, which is hampering rapid …
[图书][B] Nutrition labelling: policy brief
World Health Organization - 2022 - books.google.com
Acknowledging that nutrition labelling policies have a dual purpose (ie to protect the health
of consumers and to ensure fair practices in food trade), this policy brief focusses on nutrition …
of consumers and to ensure fair practices in food trade), this policy brief focusses on nutrition …
Bedaquiline- and clofazimine- selected Mycobacterium tuberculosis mutants: further insights on resistance driven largely by Rv0678
J Snobre, MC Villellas, N Coeck, W Mulders… - Scientific Reports, 2023 - nature.com
Drug-resistant tuberculosis is a serious global health threat. Bedaquiline (BDQ) is a
relatively new core drug, targeting the respiratory chain in Mycobacterium tuberculosis (Mtb) …
relatively new core drug, targeting the respiratory chain in Mycobacterium tuberculosis (Mtb) …
Variants associated with Bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naïve TB …
Abstract Background Mutations in the Rv0678, pepQ and atpE genes of Mycobacterium
tuberculosis (MTB) have been reported to be associated with reduced antimycobacterial …
tuberculosis (MTB) have been reported to be associated with reduced antimycobacterial …