Inflammatory mechanisms in tendinopathy–towards translation

NL Millar, GAC Murrell, IB McInnes - Nature reviews rheumatology, 2017 - nature.com
Tendinopathy is a multifactorial spectrum of tendon disorders that affects different
anatomical sites and is characterized by activity-related tendon pain. These disorders are …

Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis

E Gracey, A Burssens, I Cambré, G Schett… - Nature reviews …, 2020 - nature.com
Mechanical loading is an important factor in musculoskeletal health and disease. Tendons
and ligaments require physiological levels of mechanical loading to develop and maintain …

Growth factor and catabolic cytokine concentrations are influenced by the cellular composition of platelet-rich plasma

EA Sundman, BJ Cole… - The American journal of …, 2011 - journals.sagepub.com
Background: Previous studies of bioactive molecules in platelet-rich plasma (PRP) have
documented growth factor concentrations that promote tissue healing. However, the effects …

Role of extracellular matrix in adaptation of tendon and skeletal muscle to mechanical loading

M Kjaer - Physiological reviews, 2004 - journals.physiology.org
Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

Tendon injury and tendinopathy: healing and repair

P Sharma, N Maffulli - JBJS, 2005 - journals.lww.com
Tendon Injury and Tendinopathy: Healing and Repair : JBJS Tendon Injury and Tendinopathy:
Healing and Repair : JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical …

Optimization of leukocyte concentration in platelet-rich plasma for the treatment of tendinopathy

TM McCarrel, T Minas, LA Fortier - JBJS, 2012 - journals.lww.com
Background: Numerous methods are available for platelet-rich plasma (PRP) generation,
but evidence defining the optimum composition is lacking. We hypothesized that leukocyte …

Structure‐function relationships in tendons: a review

M Benjamin, E Kaiser, S Milz - Journal of anatomy, 2008 - Wiley Online Library
The purpose of the current review is to highlight the structure‐function relationship of
tendons and related structures to provide an overview for readers whose interest in tendons …

Reparative and maladaptive inflammation in tendon healing

V Arvind, AH Huang - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
Tendon injuries are common and debilitating, with non-regenerative healing often resulting
in chronic disease. While there has been considerable progress in identifying the cellular …

The role of mechanobiology in tendon healing

ML Killian, L Cavinatto, LM Galatz… - Journal of shoulder and …, 2012 - Elsevier
Mechanical cues affect tendon healing, homeostasis, and development in a variety of
settings. Alterations in the mechanical environment are known to result in changes in the …

Temporal growth factor release from platelet‐rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene …

T McCarrel, L Fortier - Journal of Orthopaedic Research, 2009 - Wiley Online Library
Platelet‐rich plasma (PRP) has generated substantial interest for tendon and ligament
regeneration because of the high concentrations of growth factors in platelet α‐granules …