Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

Motivation Ageing is a biological and psychosocial process related to diseases and
mortality. It correlates with changes in DNA methylation (DNAm) in all human tissues …

Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration
(EGAA) are biomarkers of physiological development and may be affected by the perinatal …

It has been noted for quite some time that DNA methylation levels decline with age. The
significance of this change remained unknown until it became possible to measure …

Although male–female differences in placental structure and function have been observed,
little is understood about their molecular underpinnings. Here, we present a mega-analysis …

Pregnancy can exacerbate or prompt the onset of stress-related disorders, such as post-
traumatic stress disorder (PTSD). PTSD is associated with heightened stress responsivity …

Identifying factors that influence fetal growth in a sex-specific manner can help unravel
mechanisms that explain sex differences in adverse neonatal outcomes and in-utero origins …

Background Gestational age is a useful proxy for assessing developmental maturity, but
correct estimation of gestational age is difficult using clinical measures. DNA methylation at …

Biological age, measured via epigenetic clocks, offers a unique and useful tool for
prevention scientists to explore the short-and long-term implications of age deviations for …