Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …

Astrocytes are essential in maintaining normal brain functions such as blood brain barrier
(BBB) homeostasis and synapse formation as the most abundant cell type in the central …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the alveoli, where
abundant alveolar macrophages (AMs) reside. How AMs respond to SARS-CoV-2 invasion …

Astrocytes are increasingly recognised as partaking in complex homeostatic mechanisms
critical for regulating neuronal plasticity following central nervous system (CNS) insults …

Immune checkpoint inhibitors (ICIs) have been increasingly used in combination for cancer
treatment but are associated with myocarditis. Here, we report that tumor-bearing mice …

Ethnopharmacological relevance Apoptosis plays an important role in cerebral ischemia-
reperfusion injury and triggers a series of pathological changes which may even be life …

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a novel evolutionarily
conserved protein present in both vertebrate and invertebrate species. MANF shows distinct …

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum-
resident protein and a secretory factor and has beneficial effects in multiple diseases …

Unsatisfactory post‐stroke recovery has long been a negative factor in the prognosis of
ischemic stroke due to the lack of pharmacological treatments. Mesenchymal stem cells …

Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine
neurotrophic factor (CDNF) are endoplasmic reticulum (ER) luminal proteins that confer …