Prevention of neurodegenerative diseases is presently a major goal for our Society and
melatonin, an unusual phylogenetically conserved molecule present in all aerobic …

Mitochondria and chloroplasts are major sources of free radical generation in living
organisms. Because of this, these organelles require strong protection from free radicals and …

Inherited neuropathies known as Charcot-Marie-Tooth (CMT) disease are genetically
heterogeneous disorders affecting the peripheral nerves, causing significant and slowly …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in
childhood. It is caused by mutations of the DMD gene, leading to progressive muscle …

Melatonin is an indolamine synthesized and secreted by the pineal gland along with other
extrapineal sources including immune system cells, the brain, skin and the gastrointestinal …

The aim of this review is to update the reader as to the association between physical
exercise and melatonin, and to clarify how the melatonin rhythm may be affected by different …

Exercise, eccentric contractions, acute trauma, and disease are all causal mechanisms of
skeletal muscle injury. After skeletal muscle is injured, it undergoes sequential phases of …

Oxidative stress is a loss of balance between the production of reactive oxygen species
during cellular metabolism and the mechanisms that clear these species to maintain cellular …

Introduction: Duchenne muscular dystrophy (DMD) is the most common, severe childhood
form of muscular dystrophy. Treatment is limited to glucocorticoids that have the benefit of …

Previous data showed that the administration of high doses of melatonin improved the
circadian system in athletes. Here, we investigated in the same experimental paradigm …