Puzzles, challenges, and information reservoir of SARS-CoV-2 quasispecies

E Domingo, B Martínez-González… - Journal of …, 2023 - Am Soc Microbiol
Upon the emergence of SARS-CoV-2 in the human population, it was conjectured that for
this coronavirus the dynamic intra-host heterogeneity typical of RNA viruses would be toned …

Behind the scenes: Centromere-driven genomic innovations in fungal pathogens

A Narayanan, MH Reza, K Sanyal - Plos Pathogens, 2024 - journals.plos.org
Adverse environmental factors challenge the existence of every living being. In nature,
sexual reproduction and meiotic recombination act to generate genetic variations that help …

Intraspecific diploidization of a halophyte root fungus drives heterosis

Z Li, Z Zhu, K Qian, B Tang, B Han, Z Zhong… - Nature …, 2024 - nature.com
How organisms respond to environmental stress is a key topic in evolutionary biology. This
study focused on the genomic evolution of Laburnicola rhizohalophila, a dark-septate …

Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans

P Vande Zande, C Gautier, N Kawar, C Maufrais… - PLoS …, 2024 - journals.plos.org
Antimicrobial drug resistance poses a global health threat, requiring a deeper
understanding of the evolutionary processes that lead to its emergence in pathogens …

: The role of whole genome duplication in evolutionary ecology

KA Segraves, TJ Anneberg - Oikos, 2024 - Wiley Online Library
Polyploid organisms are common and can be found across the tree of life. A key question is
to understand how and why these polyploid lineages become established and persist in …

Enhanced oxidative stress resistance in Ustilago maydis and its implications on the virulence

J Cuamatzi-Flores, M Colón-González… - International …, 2024 - Springer
The phytopathogenic fungus Ustilago maydis causes corn smut by suppressing host plant
defenses, including the oxidative burst response. While many studies have investigated how …

[HTML][HTML] Comparative modeling reveals the molecular determinants of aneuploidy fitness cost in a wild yeast model

J Rojas, J Hose, HA Dutcher, M Place, JF Wolters… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Although implicated as deleterious in many organisms, aneuploidy can underlie rapid
phenotypic evolution. However, aneuploidy will only be maintained if the benefit outweighs …

[HTML][HTML] Whole-genome duplication in the Multicellularity Long Term Evolution Experiment

K Tong, S Datta, V Cheng, DJ Haas, S Gourisetti… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Whole-genome duplication (WGD) is widespread across eukaryotes and can promote
adaptive evolution 1-4. However, given the instability of newly-formed polyploid genomes 5 …

The transcriptomic and proteomic ramifications of segmental amplification

RK Fritts, CC Ebmeier, SD Copley - bioRxiv, 2023 - biorxiv.org
Gene duplication and subsequent amplification can drive adaptation by rapidly increasing
the cellular dosage of critical gene products. Gene duplication events often encompass …

Further diversity in the origins of fish antifreeze proteins

KV Ewart - The FEBS Journal - Wiley Online Library
Shifts in environmental conditions can impose strong selection for adaptive traits. During the
Cenozoic era, as the oceans cooled, many marine teleost fish species were at risk of …