Cancer cells co-evolve with retrotransposons to mitigate viral mimicry
Overexpression of repetitive elements is an emerging hallmark of human cancers. Diverse
repeats can mimic viruses by replicating within the cancer genome through …
repeats can mimic viruses by replicating within the cancer genome through …
Subcellular location of L1 retrotransposon-encoded ORF1p, reverse transcription products, and DNA sensors in lupus granulocytes
F Moadab, S Sohrabi, X Wang, R Najjar, JC Wolters… - Mobile dna, 2024 - Springer
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with an
unpredictable course of recurrent exacerbations alternating with more stable disease. SLE is …
unpredictable course of recurrent exacerbations alternating with more stable disease. SLE is …
Repeats mimic pathogen-associated patterns across a vast evolutionary landscape
An emerging hallmark across many human diseases-such as cancer, autoimmune and
neurodegenerative disorders–is the aberrant transcription of typically silenced repetitive …
neurodegenerative disorders–is the aberrant transcription of typically silenced repetitive …