Aryl sulfonyl chlorides (eg Ts‐Cl) are beloved of organic chemists as the most commonly
used SVI electrophiles, and the parent sulfuryl chloride, O2SVICl2, has also been relied on …

Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Several combinatorial methods have been developed to create focused or diverse chemical
libraries with a wide range of linear or macrocyclic chemical molecules: peptides, non …

Direct interfacing of nanosensors onto biomaterials could impact health quality monitoring
and adaptive threat detection. Graphene is capable of highly sensitive analyte detection due …

Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Fluorescence microscopy is a powerful quantitative tool for exploring regulatory networks in
single cells. However, the number of molecular species that can be measured …

Sulfur fluoride exchange (SuFEx) has emerged as the new generation of click chemistry. We
report here a SuFEx-enabled, agnostic approach for the discovery and optimization of …

Combinatorial approaches to the discovery of new functional molecules are well established
among chemists and biologists, inspired in large measure by the modular composition of …

Antibodies have been extensively used as capture and detection reagents in diagnostic
applications of proteomics‐based technologies. Proteomic assays need high sensitivity and …

Optical sensors represent a vitally important class of analytical tools that have been used to
provide chemical information ranging from analyte concentration and binding kinetics to …