Biomedical applications of hydrogels in drug delivery system: An update

P Kesharwani, A Bisht, A Alexander, V Dave… - Journal of Drug Delivery …, 2021 - Elsevier
Conventional drug delivery system generally deals with the issues involving repeated
dosing and systemic toxicities. Since few decades, hydrogels have played a significant role …

Injectable thermosensitive hydrogel-based drug delivery system for local cancer therapy

Y Xiao, Y Gu, L Qin, L Chen, X Chen, W Cui, F Li… - Colloids and Surfaces B …, 2021 - Elsevier
Injectable thermosensitive hydrogel has been regarded as attractive drug delivery system,
which displays a sol-gel phase transition upon injection in response to temperature …

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

W Li, Z Liu, F Fontana, Y Ding, D Liu… - Advanced …, 2018 - Wiley Online Library
In the past two decades, porous silicon (PSi) has attracted increasing attention for its
potential biomedical applications. With its controllable geometry, tunable nanoporous …

Injectable hydrogels for localized cancer therapy

D Fan, Y Tian, Z Liu - Frontiers in chemistry, 2019 - frontiersin.org
Traditional intravenous chemotherapy is relative to many systemic side effects, including
myelosuppression, liver or kidney dysfunction, and neurotoxicity. As an alternative method …

Multifunctional smart hydrogels: Potential in tissue engineering and cancer therapy

X Li, X Su - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
In recent years, clinical applications have been proposed for various hydrogel products.
Hydrogels can be derived from animal tissues, plant extracts and/or adipose tissue …

Thermo-responsive hydrogels for cancer local therapy: Challenges and state-of-art

D Rafael, MMR Melendres, F Andrade… - International journal of …, 2021 - Elsevier
Despite the enormous efforts done by the scientific community in the last decades, advanced
cancer is still considered an incurable disease. New formulations are continuously under …

Paclitaxel drug delivery systems: Focus on nanocrystals' surface modifications

R Haddad, N Alrabadi, B Altaani, T Li - Polymers, 2022 - mdpi.com
Paclitaxel (PTX) is a chemotherapeutic agent that belongs to the taxane family and which
was approved to treat various kinds of cancers including breast cancer, ovarian cancer …

Multiple local therapeutics based on nano-hydrogel composites in breast cancer treatment

RZ Tang, ZZ Liu, SS Gu, XQ Liu - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
The locoregional recurrence of breast cancer after tumor resection represents several
clinical challenges, and conventional post-surgical adjuvant therapeutics always bring about …

Platelet membrane-cloaked paclitaxel-nanocrystals augment postoperative chemotherapeutical efficacy

D Mei, L Gong, Y Zou, D Yang, H Liu, Y Liang… - Journal of Controlled …, 2020 - Elsevier
Chemotherapy post cancer surgery has important clinical significance for reducing the
chance of recurrent-metastasis. However, postoperative chemotherapy efficacy is hampered …

A novel long-acting azathioprine polyhydroxyalkanoate nanoparticle enhances treatment efficacy for systemic lupus erythematosus with reduced side effects

J Hu, M Wang, X Xiao, B Zhang, Q Xie, X Xu, S Li… - Nanoscale, 2020 - pubs.rsc.org
Chemical immunosuppressants have been widely used for the treatment of systemic lupus
erythematosus (SLE). However, these small chemical drugs suffer from poor solubility, short …