Bone defects pose a heavy burden on patients, orthopedic surgeons, and public health
resources. Various pathological conditions cause bone defects including trauma, tumors …

Fractures are the most common large-organ, traumatic injuries to humans. The repair of
bone fractures is a postnatal regenerative process that recapitulates many of the ontological …

Purpose of review Bone fracture healing is a complex physiological process relying on
numerous cell types and signals. Inflammatory factors secreted by immune cells help to …

Immune responses are crucial not only for host defence against pathogens but also for
tissue maintenance and repair after injury. Lymphocytes are involved in the healing process …

Abstract Purpose of Review This review summarizes research on the physiological changes
that occur with aging and the resulting effects on fracture healing. Recent Findings Aging …

Abstract Purpose of Review In the process of bone fracture healing, inflammation is thought
to be an essential process that precedes bone formation and remodeling. We review recent …

Intersectionality, the theory named by Kimberlé Crenshaw, outlines how multiple elements of
an individual's social identity overlap to create and preserve societal inequalities and …

Over the past years, basic findings in cancer research have revealed metabolic symbiosis
between different cell types to cope with high energy demands under limited nutrient …

Fractures are the most common large organ trauma in humans. The initial inflammatory
response promotes bone healing during the initial post-fracture phase, but chronic and …

Although previous RNA sequencing methods have been widely used in orthopedic research
and have provided ideas for therapeutic strategies, the specific mechanisms of some …