Functional and nutraceutical foods provide an alternative way to improve immune function to
aid in the management of various diseases. Traditionally, many medicinal products have …

The ventilation of the lung ranges between 1,000 and 21,000 liters per 24 hours in humans
depending on body size and physical activity. This exposes the extensive epithelial surface …

Asthma is a chronic disease most commonly associated with allergy and type 2
inflammation. However, the mechanisms that link airway inflammation to the structural …

Asthma and chronic obstructive pulmonary disease are characterized by chronic airway
inflammation. Studies using bronchoalveolar lavage (BAL) have shown an increased …

Background Although inhaled glucocorticosteroids are recommended for persistent asthma,
their long-term effect on recent onset, mild, persistent asthma has yet to be established …

Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and …

To study the mechanisms and kinetics underlying the development of increased airway
responsiveness (AR) after allergic sensitization, animal models have been invaluable. Using …

Cellular inflammation of the airways with eosinophils and neutrophils is a characteristic
feature of asthma and is considered relevant to the pathogenesis of the disease. Studies of …

IgE plays an important role in allergic asthma. We hypothesized that reducing IgE in the
airway mucosa would reduce airway inflammation. Forty-five patients with mild to moderate …

Asthma is characterized by the presence of an inflammatory cell infiltrate in the bronchial
mucosa consisting of activated mast cells, eosinophils, and T cells. Several cytokines are …