The gastrointestinal tract has the important task of absorbing nutrients, a complex process
that requires an intact barrier allowing the passage of nutrients but that simultaneously …

Serovars of Salmonella enterica cause both gastrointestinal and systemic diseases in a
broad range of mammalian hosts, including humans. Salmonella virulence depends in part …

Critical cancer pathways often cannot be targeted because of limited efficiency crossing cell
membranes. Here we report the development of a Salmonella-based intracellular delivery …

Salmonellae invasion and intracellular replication within host cells result in a range of
diseases, including gastroenteritis, bacteraemia, enteric fever and focal infections. In recent …

Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

Selective autophagy can be mediated via receptor molecules that link specific cargoes to the
autophagosomal membranes decorated by ubiquitin-like microtubule-associated protein …

Infections are estimated to contribute to 20% of all human tumours. These are mainly caused
by viruses, which explains why a direct bacterial contribution to cancer formation has been …

INTRODUCTION In the arms race between pathogen and host, infecting microbes often
escape extracellular defense mechanisms to exploit the nutrient-rich intracellular …

Caspases are either apoptotic or inflammatory. Among inflammatory caspases, caspase-1
and-11 trigger pyroptosis, a form of programmed cell death. Whereas both can be …

Shigella is a major cause of bacillary dysentery world-wide. It is divided into four species,
named S. flexneri, S. sonnei, S. dysenteriae, and S. boydii, which are distinct genomically …