Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Improvements in genomic and molecular methods are expanding the range of potential
applications for circulating tumour DNA (ctDNA), both in a research setting and as a'liquid …

Oesophageal cancer is the sixth most common cause of cancer-related death worldwide
and is therefore a major global health challenge. The two major subtypes of oesophageal …

Summary Background Treatment of dysplastic Barrett's oesophagus prevents progression to
adenocarcinoma; however, the optimal diagnostic strategy for Barrett's oesophagus is …

Because the esophagus is easily accessible with endoscopy, early diagnosis and curative
treatment of esophageal cancer is possible. However, diagnosis is often delayed because …

Background Endoscopic surveillance is recommended for patients with Barrett's
oesophagus because, although the progression risk is low, endoscopic intervention is highly …

We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

Cancer development is a complex process driven by inherited and acquired molecular and
cellular alterations. Prevention is the holy grail of cancer elimination, but making this a reality …

Oesophageal cancer is currently the sixth commonest source of cancer-associated death
across the world: 572 034 new cases and 508 585 mortalities were reported in 2018. 1 …