Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
From basics to clinical: a comprehensive review on spinal cord injury
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …
individuals each year. Over the past decades an enormous progress has been made in our …
Restoring function after spinal cord injury: towards clinical translation of experimental strategies
Spinal cord injury is currently incurable and treatment is limited to minimising secondary
complications and maximising residual function by rehabilitation. Improved understanding of …
complications and maximising residual function by rehabilitation. Improved understanding of …
Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon
JW Rowland, GWJ Hawryluk, B Kwon, MG Fehlings - Neurosurgical focus, 2008 - thejns.org
This review summarizes the current understanding of spinal cord injury pathophysiology and
discusses important emerging regenerative approaches that have been translated into …
discusses important emerging regenerative approaches that have been translated into …
Therapeutic interventions after spinal cord injury
Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …
Restoration of sensorimotor functions after spinal cord injury
The purpose of this review is to discuss the achievements and perspectives regarding
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …
Concise review: a comprehensive analysis of reported adverse events in patients receiving unproven stem cell-based interventions
G Bauer, M Elsallab… - Stem cells translational …, 2018 - academic.oup.com
The promise of stem cell (SC) therapies to restore functions of damaged tissues and organs
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
Autologous olfactory ensheathing cell transplantation in human paraplegia: a 3-year clinical trial
A Mackay-Sim, F Feron, J Cochrane… - Brain, 2008 - academic.oup.com
Olfactory ensheathing cells show promise in preclinical animal models as a cell
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …
transplantation therapy for repair of the injured spinal cord. This is a report of a clinical trial of …
Stem cell technology for neurodegenerative diseases
JS Lunn, SA Sakowski, J Hur… - Annals of neurology, 2011 - Wiley Online Library
Over the past 20 years, stem cell technologies have become an increasingly attractive
option to investigate and treat neurodegenerative diseases. In the current review, we …
option to investigate and treat neurodegenerative diseases. In the current review, we …
Cell therapies for spinal cord injury: a review of the clinical trials and cell-type therapeutic potential
BF Ribeiro, BC da Cruz, BM de Sousa, PD Correia… - Brain, 2023 - academic.oup.com
Spinal cord injury (SCI) is an as yet untreatable neuropathology that causes severe
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …
dysfunction and disability. Cell-based therapies hold neuroregenerative and neuroprotective …