The intestinal microbiota fuelling metabolic inflammation

H Tilg, N Zmora, TE Adolph, E Elinav - Nature Reviews Immunology, 2020 - nature.com
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function

BL Tan, ME Norhaizan - Nutrients, 2019 - mdpi.com
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes

TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

The alterations in and the role of the Th17/Treg balance in metabolic diseases

S Zhang, X Gang, S Yang, M Cui, L Sun, Z Li… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammation plays an important role in the development of metabolic diseases.
These include obesity, type 2 diabetes mellitus, and metabolic dysfunction-associated fatty …

The differential roles of T cells in non-alcoholic fatty liver disease and obesity

MA Van Herck, J Weyler, WJ Kwanten… - Frontiers in …, 2019 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) constitutes a spectrum of disease states
characterized by hepatic steatosis and is closely associated to obesity and the metabolic …

Pathophysiology and mechanisms of nonalcoholic fatty liver disease

JT Haas, S Francque, B Staels - Annual review of physiology, 2016 - annualreviews.org
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver disorders
characterized by abnormal hepatic fat accumulation, inflammation, and hepatocyte …

Obesity and cognitive decline: role of inflammation and vascular changes

JCD Nguyen, AS Killcross, TA Jenkins - Frontiers in neuroscience, 2014 - frontiersin.org
The incidence of obesity in middle age is increasing markedly, and in parallel the
prevalence of metabolic disorders including cardiovascular disease and type II diabetes is …

Role of “Western diet” in inflammatory autoimmune diseases

A Manzel, DN Muller, DA Hafler, SE Erdman… - Current allergy and …, 2014 - Springer
Developed societies, although having successfully reduced the burden of infectious
disease, constitute an environment where metabolic, cardiovascular, and autoimmune …

Psoriasis and metabolic syndrome: implications for the management and treatment of psoriasis

JJ Wu, A Kavanaugh, MG Lebwohl… - Journal of the …, 2022 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities
in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …

[HTML][HTML] Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C

S Tanwar, F Rhodes, A Srivastava… - World journal of …, 2020 - ncbi.nlm.nih.gov
At present chronic liver disease (CLD), the third commonest cause of premature death in the
United Kingdom is detected late, when interventions are ineffective, resulting in …