Modeling neurodevelopmental cognitive deficits in tasks with cross‐species translational validity
ZA Cope, SB Powell, JW Young - Genes, Brain and Behavior, 2016 - Wiley Online Library
Numerous psychiatric disorders whose cognitive dysfunction links to functional outcome
have neurodevelopmental origins including schizophrenia, autism and bipolar disorder …
have neurodevelopmental origins including schizophrenia, autism and bipolar disorder …
Functional coding variation in the presynaptic dopamine transporter associated with neuropsychiatric disorders drives enhanced motivation and context-dependent …
GL Davis, A Stewart, GD Stanwood… - Behavioural brain …, 2018 - Elsevier
Recent genetic analyses have provided evidence that clinical commonalities associated
with different psychiatric diagnoses often have shared mechanistic underpinnings. The …
with different psychiatric diagnoses often have shared mechanistic underpinnings. The …
Putative therapeutic targets for symptom subtypes of adult ADHD: D4 receptor agonism and COMT inhibition improve attention and response inhibition in a novel …
A Tomlinson, B Grayson, S Marsh, A Hayward… - European …, 2015 - Elsevier
Prefrontal cortical dopamine plays an important role in cognitive control, specifically in
attention and response inhibition; the core deficits in ADHD. We have previously shown that …
attention and response inhibition; the core deficits in ADHD. We have previously shown that …
Proline‐rich polypeptides (Colostrinin®/COLOCO®) modulate BDNF concentration in blood affecting cognitive function in adults: A double‐blind randomized …
H Banasiak‐Cieślar, D Wiener… - Food Science & …, 2023 - Wiley Online Library
Proline‐rich polypeptides (PRPs complex also known as COLOCO®, Colostrinin®) consist
of low‐molecular weight peptides ranging up to 10 kDa, isolated from the bovine colostrum …
of low‐molecular weight peptides ranging up to 10 kDa, isolated from the bovine colostrum …
The divergent impact of COMT Val158Met on executive function in children with and without attention‐deficit/hyperactivity disorder
J Jin, L Liu, Q Gao, RCK Chan, H Li… - Genes, Brain and …, 2016 - Wiley Online Library
Children with attention‐deficit/hyperactivity disorder (ADHD) usually display deficits in
executive function (EF), which are primarily mediated by prefrontal cortex (PFC). The …
executive function (EF), which are primarily mediated by prefrontal cortex (PFC). The …
Gene–exercise interaction on brain health in children with overweight/obesity: the ActiveBrains randomized controlled trial
A Plaza-Florido, I Esteban-Cornejo… - Journal of Applied …, 2023 - journals.physiology.org
We investigated the interaction between a genetic score and an exercise intervention on
brain health in children with overweight/obesity. One hundred one children with …
brain health in children with overweight/obesity. One hundred one children with …
The distribution of parent‐reported attention‐deficit/hyperactivity disorder and subclinical autistic traits in children with and without an ADHD diagnosis
Background Autistic traits are often reported to be elevated in children diagnosed with
attention‐deficit/hyperactivity disorder (ADHD). However, the distribution of subclinical …
attention‐deficit/hyperactivity disorder (ADHD). However, the distribution of subclinical …
Influence of the COMT val108/158met polymorphism on continuous performance task indices
Y Park, ID Waldman - Neuropsychologia, 2014 - Elsevier
Abstract The Continuous Performance Task (CPT) is a widely-used measure of sustained
attention and impulsivity. Deficits in CPT performance have been found in several …
attention and impulsivity. Deficits in CPT performance have been found in several …
The association between the catechol-O-methyltransferase Val108/158Met polymorphism and hyperactive–impulsive and inattentive symptoms in youth
Rationale Hyperactivity, impulsivity, and inattention are major symptoms occurring in
attention-deficit/hyperactivity disorder. This disorder is highly heritable, multifactorial …
attention-deficit/hyperactivity disorder. This disorder is highly heritable, multifactorial …
Influence of DAT1 and COMT variants on neural activation during response inhibition in adolescents with attention-deficit/hyperactivity disorder and healthy controls
Background. Impairment of response inhibition has been implicated in attention-
deficit/hyperactivity disorder (ADHD). Dopamine neurotransmission has been linked to the …
deficit/hyperactivity disorder (ADHD). Dopamine neurotransmission has been linked to the …