The mouse brain is the most extensively studied brain of all species. We performed an
exhaustive review of the literature to establish our current state of knowledge on cell …

Alzheimer's disease (AD) is marked by the presence of extracellular amyloid beta (Aβ)
plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the …

By 2050, the aging population is predicted to expand by over 100%. Considering this rapid
growth, and the additional strain it will place on healthcare resources because of age …

Maintenance of the endothelial blood-brain-barrier (BBB) through Wnt/β-catenin signalling is
essential for neuronal function. The cells however, providing Wnt growth factors at the adult …

Astrocytes have essential roles in the central nervous system and are also implicated in the
pathogenesis of neurodegenerative disease. Forming non‐overlapping domains, astrocytes …

Astrocytes possess different morphological characteristics depending on the cerebral region
in which they are found. However, none of the current astrocytic markers can label all …

Astrocyte pathology occurs in association with Alzheimer's disease (AD) and in brain
ageing, but is poorly characterised. We sought to define the detailed cellular pathology of …

Astroglia represent a class of heterogeneous, in form and function, cells known as
astrocytes, which provide for homoeostasis and defence of the central nervous system …

Morphological aging of astrocytes was investigated in entorhinal cortex (EC), dentate gyrus
(DG), and cornu ammonis 1 (CA1) regions of hippocampus of male SV129/C57BL6 mice of …

Understanding the role of astrocytes in the central nervous system has changed dramatically
over the last decade. The accumulating findings indicate that glial cells are involved not only …