The intricate dance of tumor evolution: Exploring immune escape, tumor migration, drug resistance, and treatment strategies

X Guo, X Bian, Y Li, X Zhu, X Zhou - … Acta (BBA)-Molecular Basis of Disease, 2024 - Elsevier
Recent research has unveiled fascinating insights into the intricate mechanisms governing
tumor evolution. These studies have illuminated how tumors adapt and proliferate by …

Targeting receptor tyrosine kinases as a novel strategy for the treatment of triple-negative breast cancer

SK Jaradat, NM Ayoub, AH Al Sharie… - Technology in Cancer …, 2024 - journals.sagepub.com
Triple-negative breast cancer (TNBC) comprises a group of aggressive and heterogeneous
breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors …

Genomic profiles of Japanese patients with vulvar squamous cell carcinoma

E Fujii, MK Kato, M Yamaguchi, D Higuchi… - Scientific Reports, 2024 - nature.com
The incidence of vulvar carcinoma varies by race; however, it is a rare disease, and its
genomic profiles remain largely unknown. This study examined the characteristics of vulvar …

The Transformative Role of 3D Culture Models in Triple-Negative Breast Cancer Research

XS Bittman-Soto, ES Thomas, ME Ganshert… - Cancers, 2024 - mdpi.com
Simple Summary This review article delves into the expanding role of 3D culture models in
advancing breast cancer biology comprehension and enhancing drug response predictions …

Breast Cancer Tissue Explants: An Approach to Develop Personalized Therapy in Public Health Services

P Carranza-Rosales, D Valencia-Mercado… - Journal of Personalized …, 2023 - mdpi.com
Breast cancer is one of the main causes of death worldwide. Lately, there is great interest in
developing methods that assess individual sensitivity and/or resistance of tumors to …

Stratification of Tamoxifen Synergistic Combinations for the Treatment of ER+ Breast Cancer

EK Zboril, JM Grible, DC Boyd, NS Hairr, TJ Leftwich… - Cancers, 2023 - mdpi.com
Simple Summary ER+ breast cancer is the most diagnosed subtype and patient prognosis
has improved in recent years thanks largely to the development of endocrine-targeting …

KPT-330 synergizes with everolimus to reduce mTORC1-overactive basal-like triple-negative breast cancer brain metastasis burden

AD Valentine - 2023 - scholarscompass.vcu.edu
Triple-negative breast cancer (TNBC), a highly metastatic breast cancer subtype, accounts
for approximately 20% of all breast cancer diagnoses. Basal-like TNBC is notably difficult to …