Glutathione-related enzymes and proteins: a review

J Vašková, L Kočan, L Vaško, P Perjési - Molecules, 2023 - mdpi.com
The tripeptide glutathione is found in all eukaryotic cells, and due to the
compartmentalization of biochemical processes, its synthesis takes place exclusively in the …

[HTML][HTML] Ascorbic acid metabolism and functions: A comparison of plants and mammals

N Smirnoff - Free Radical Biology and Medicine, 2018 - Elsevier
Ascorbic acid is synthesised by eukaryotes, the known exceptions being primates and some
other animal groups which have lost functional gulonolactone oxidase. Prokaryotes do not …

Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial

S JamaliMoghadamSiahkali, B Zarezade… - European journal of …, 2021 - Springer
Background Vitamin C is an essential water-soluble nutrient that functions as a key
antioxidant and has been proven to be effective for boosting immunity. In this study, we …

Recent trends in carbon nanomaterial-based electrochemical sensors for biomolecules: A review

C Yang, ME Denno, P Pyakurel, BJ Venton - Analytica chimica acta, 2015 - Elsevier
Carbon nanomaterials are advantageous for electrochemical sensors because they
increase the electroactive surface area, enhance electron transfer, and promote adsorption …

A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Aging of cerebral white matter

H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Does vitamin C influence neurodegenerative diseases and psychiatric disorders?

J Kocot, D Luchowska-Kocot, M Kiełczykowska, I Musik… - Nutrients, 2017 - mdpi.com
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit
C helps maintain integrity and function of several processes in the central nervous system …

Glutathione dysregulation and the etiology and progression of human diseases

N Ballatori, SM Krance, S Notenboom, S Shi, K Tieu… - 2009 - degruyter.com
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …

Regulation of the epigenome by vitamin C

JI Young, S Züchner, G Wang - Annual review of nutrition, 2015 - annualreviews.org
Emerging evidence suggests that ascorbate, the dominant form of vitamin C under
physiological pH conditions, influences activity of the genome via regulating epigenomic …

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

DN Hauser, TG Hastings - Neurobiology of disease, 2013 - Elsevier
The pathogenic mechanisms that underlie Parkinson's disease remain unknown. Here, we
review evidence from both sporadic and genetic forms of Parkinson's disease that implicate …