HIV-1 persists in infected individuals despite years of antiretroviral therapy (ART), due to the
formation of a stable and long-lived latent viral reservoir. Early ART can reduce the latent …

It is widely accepted that effective human immunodeficiency virus (HIV) vaccines need to
elicit a range of responses, including neutralising antibodies and T-cells. In natural HIV …

Both neutralization and antibody-dependent cellular cytotoxicity (ADCC) may be required for
effective protection against HIV-1 infection. While there is extensive information on the …

The evolution of human immunodeficiency virus type 1 (HIV-1) with respect to co-receptor
utilization has been shown to be relevant to HIV-1 pathogenesis and disease. The CCR5 …

Pathogen-driven selection and past interbreeding with archaic human lineages have
resulted in differences in human leukocyte antigen (HLA)-allele frequencies between …

In chronic HIV infection, CD8+ T cell responses to Gag are associated with lower viral loads,
but longitudinal studies of HLA-restricted CD8+ T cell-driven selection pressure in Gag from …

To investigate whether distinct populations have differing human immunodeficiency virus
type 1 (HIV) neutralizing antibody responses, we compared 20 women from Tanzania's HIV …

Disclosed are novel benzamide compounds and the uses thereof for treating diseases and
disorders in a patient in need thereof by increasing cellular levels of A3G and/or other …

The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef is heavily targeted
by CD8+ T lymphocytes (CTLs) during acute infection and therefore is included in many …

Fig. 1. Phylogenetic tree based on HIV-1 polymerase sequences from the source and index
patients. Partial polymerase gene tree estimated by the neighbor-joining method with a …