Cabbage juice protect against Lead-induced liver and kidney damage in male Wistar rat

JN Asiwe, TA Kolawole, KK Anachuna, EI Ebuwa… - Biomarkers, 2022 - Taylor & Francis
Aim Liver and kidney has been implicated in Lead toxicity and this has been linked to
oxidative damage. On the other hand, cabbage is one of the widely consumed vegetables …

Ginkgo biloba Supplement Reverses Lead (II) Acetate–Induced Haematological Imbalances, and Hepatic and Renal Dysfunctions in Male Wistar Rat

JN Asiwe, TME Daubry, IA Okon, AE Akpotu… - Biological trace element …, 2022 - Springer
Lead is a heavy metal abundant in nature that causes haematological imbalances, and
hepatic and renal dysfunction, and this imbalance has been linked to oxidative stress …

Ginkgo biloba supplement abates lead-induced endothelial and testicular dysfunction in Wistar rats via up-regulation of Bcl-2 protein expression, pituitary-testicular …

JN Asiwe, EN Ekene, LC Agbugba, EG Moke… - Journal of Trace …, 2023 - Elsevier
Background Apoptotic and oxido-inflammatory pathways have been found to be up-
regulated in lead acetate poisoning which has been associated to endothelial and testicular …

[HTML][HTML] Inhibition of oxido-inflammatory and apoptotic pathway is involved in the protective effect of Ginkgo biloba supplement in cyclosporine-A induced vascular …

JN Asiwe, SI Ovuakporaye, B Ben-Azu… - Pharmacological …, 2023 - Elsevier
Abstract Background Cyclosporine (Cs-A), an immunosuppressant drug used to prevent
organ rejection in patients receiving organ transplants, has been linked to cardiovascular …

Co-administration of metformin and/or glibenclamide with losartan reverse NG-nitro-l-arginine-methyl ester-streptozotocin-induced hypertensive diabetes and …

EG Moke, EKI Omogbai, SDE Osagie-Eweka… - Microvascular …, 2023 - Elsevier
Over the years, there have been opinions on whether to reduced blood pressure (BP) to a
different levels in patients with diabetes mellitus. Hence, this study investigated the efficacy …

Ginkgo biloba modulates ET-I/NO signalling in Lead Acetate induced rat model of endothelial dysfunction: Involvement of oxido-inflammatory mediators

JN Asiwe, GD Yovwin, NE Ekene… - International Journal …, 2024 - Taylor & Francis
This study investigated the modulatory effect of Ginkgo biloba extract on lead acetate-
induced endothelial dysfunction. Animals were administered GBE (50 mg/kg and 100 mg/kg …

Terminalia catappa attenuates phenylhydrazine-induced anaemia and hepato-renal toxicity in male Wistar rat by boosting blood cells, modulation of lipoproteins and up …

E Umoren, JN Asiwe, IA Okon, A Levi Amangieka… - Biomarkers, 2023 - Taylor & Francis
Aim This study investigated the haematinic, antihyperlipidaemic, hepato-renal protective
effects of Terminalia catappa aqueous leaf extract on male Wistar rats exposed to …

[HTML][HTML] Pleiotropic attenuating effect of Ginkgo biloba against isoprenaline-induced myocardial infarction via improving Bcl-2/mTOR/ERK1/2/Na+, K+-ATPase …

JN Asiwe, AA Ojetola, NE Ekene, E Osirim… - Chinese Herbal …, 2024 - Elsevier
Objective Myocardial infarction (MI) is linked to an imbalance in the supply and demand of
blood oxygen in the heart muscles. Beta-blockers and calcium antagonists are just two of the …

The effect of ethanol leaf extract of Cnidosculus Aconitifolius on cardiorenal functions in hypertensive and normotensive male Wistar rats

DI Alawode, JN Asiwe, EG Moke… - International journal of …, 2021 - ijns.sums.ac.ir
Background: Cnidoscolus aconitifolius is widely used by traditional healers in treating
plethora of ailments either alone, in combination with other therapeutic agents or as …

Effect of diabetes mellitus and hypertension on osmotic fragility and hemorheological factors in male Wistar rats

DE Okonofua, JN Asiwe, KK Anachuna… - Biology, medicine, & …, 2021 - sciencebiology.org
Diabetes mellitus is a common risk factor for erythrocyte osmotic stress. This study was
aimed at exploring the effect of streptozotocin (STZ)-induced diabetes mellitus and salt …