The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …

A novel series of α-cyano indolylchalcones was prepared, and their chemical structures
were confirmed based on the different spectral data. Among them, compound 7f was …

With the increasing incidence of cancer worldwide, the prevention and treatment of cancer
have garnered considerable scientific attention. Traditional chemotherapeutic drugs are …

Abstract A series of 1, 3, 4-thiadiazole derivatives were designed and synthesized using N-
(4-nitrophenyl) acetohydrazonoyl bromide and 1-[3, 5-dimethyl-1-(4-nitrophenyl)-1 H …

The drug resistance became the major challenge in the antimicrobial and anticancer drugs
therapy. Therefore, there is an urgent need to looking for new types of antimicrobial and …

Chalcones are interesting anticancer drug candidates which have attracted much interest
due to their unique structure and their extensive biological activity. Various functional …

Seventeen new furan‐substituted thiadiazolyl hydrazone derivatives bearing 4‐nitrophenyl
moiety were designed, synthesized and tested for their in vitro antimicrobial activity …

A new series of bis-chalcones 5-10 has been prepared by the condensation reaction of one
equivalent of bis (acetophenones) 3a-f with two equivalents of 1, 3-diphenyl-1H-pyrazole-4 …

The current study involves the design and synthesis of a newly synthesized pyrrolo [2, 3-d]
pyrimidine derivatives to contain chlorine atoms in positions 4 and 6 and trichloromethyl …

A facile and efficient route for the synthesis of novel 4H-pyrazolo [3, 4-f] indolizine-4, 9 (2H)-
dione derivatives was investigated and confirmed as a robust method. 2-Acetyl pyrrole was …