Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous
thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently …

Immunologic research into pathogenic mechanisms operating in autoimmune-mediated
atherosclerosis initially focused on adaptive immunity. Current interest is directed to more …

Oxidative modification of low-density lipoprotein (LDL) is one of the earliest events in
atherosclerosis. Oxidized LDL (oxLDL) represents a variety of modification of both lipid and …

Oxidized low-density lipoprotein (oxLDL) is thought to promote atherosclerosis through
complex inflammatory and immunologic mechanisms that lead to lipid dysregulation and …

β 2-glycoprotein I (β 2-GPI) is a major antigen for antiphospholipid antibodies (Abs, aPL)
present in patients with antiphospholipid syndrome (APS). We recently reported (J. Lipid …

Objective—In periodontitis, overgrowth of Gram-negative bacteria and access of
lipopolysaccharide (LPS) to circulation may activate macrophages leading to foam cell …

Atherosclerosis is a chronic inflammatory disease and a leading cause of human mortality.
The lesional microenvironment contains a complex accumulation of variably oxidized lipids …

Antiphospholipid syndrome (APS) is characterized by the presence of pathogenic
autoantibodies against β2-glycoprotein-I (β2GPI). The factors causing production of anti …

Periodontitis is bacterial infection of tooth-supporting tissues leading to inflammation and,
subsequently, to loss of teeth. It is one of the most common infections worldwide. Recent …

It is 20 years since the use of a radioimmunoassay enabled an association to be described
between antibodies to the anionic phospholipid cardiolipin and a set of clinical features [1] …