Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

The vertebrate immune system is comprised of numerous distinct and interdependent
components. Every component has its own inherent protective value, and the final …

Mucus clearance is the primary defense mechanism that protects airways from inhaled
infectious and toxic agents. In the current gel-on-liquid mucus clearance model, a mucus gel …

Mucus is tenacious. It sticks to most particles, preventing their penetration to the epithelial
surface. Multiple low-affinity hydrophobic interactions play a major role in these adhesive …

Airway epithelium contributes significantly to the barrier function of airway tract. Mucociliary
escalator, intercellular apical junctional complexes which regulate paracellular permeability …

The first practice parameter on exercise-induced bronchoconstriction (EIB) was published in
2010. This updated practice parameter was prepared 5 years later. In the ensuing years …

Epithelial salt and water secretion serves a variety of functions in different organ systems,
such as the airways, intestines, pancreas, and salivary glands. In cystic fibrosis (CF), the …

Recent evidence suggests that the airway mucus gel layer may be impermeable to the viral
and synthetic gene vectors used in past inhaled gene therapy clinical trials for diseases like …

Epithelial tissues protecting organs from the environment are the first-line of defense against
pathogens. Therefore, efficient repair mechanisms after injury are crucial to maintain …

SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that
reached pandemic proportions among the human population within months. The reasons for …