Development of the thyroid gland
M Nilsson, H Fagman - Development, 2017 - journals.biologists.com
Thyroid hormones are crucial for organismal development and homeostasis. In humans,
untreated congenital hypothyroidism due to thyroid agenesis inevitably leads to cretinism …
untreated congenital hypothyroidism due to thyroid agenesis inevitably leads to cretinism …
Prostate organogenesis: tissue induction, hormonal regulation and cell type specification
R Toivanen, MM Shen - Development, 2017 - journals.biologists.com
Prostate organogenesis is a complex process that is primarily mediated by the presence of
androgens and subsequent mesenchyme-epithelial interactions. The investigation of …
androgens and subsequent mesenchyme-epithelial interactions. The investigation of …
Medullary thyroid carcinoma beyond surgery: advances, challenges, and perspectives
L Ceolin, MA da Silveira Duval… - Endocrine-related …, 2019 - erc.bioscientifica.com
Medullary thyroid carcinoma (MTC) is a rare type of tumor that originates from thyroid C cells
and accounts for 2–4% of all malignant thyroid neoplasms. MTC may occur sporadically or …
and accounts for 2–4% of all malignant thyroid neoplasms. MTC may occur sporadically or …
Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development
ME Magaletta, M Lobo, EM Kernfeld, H Aliee… - Nature …, 2022 - nature.com
Maldevelopment of the pharyngeal endoderm, an embryonic tissue critical for patterning of
the pharyngeal region and ensuing organogenesis, ultimately contributes to several classes …
the pharyngeal region and ensuing organogenesis, ultimately contributes to several classes …
Calcitonin: Current concepts and differential diagnosis
A Kiriakopoulos, P Giannakis… - … in endocrinology and …, 2022 - journals.sagepub.com
Calcitonin (CT) is most effectively produced by the parafollicular cells of the thyroid gland. It
acts through the calcitonin receptor (CTR), a seven-transmembrane class II G-protein …
acts through the calcitonin receptor (CTR), a seven-transmembrane class II G-protein …
A comprehensive review on MEN2B
F Castinetti, J Moley, L Mulligan… - Endocrine-Related …, 2018 - erc.bioscientifica.com
MEN2B is a very rare autosomal dominant hereditary tumor syndrome associated with
medullary thyroid carcinoma (MTC) in 100% cases, pheochromocytoma in 50% cases and …
medullary thyroid carcinoma (MTC) in 100% cases, pheochromocytoma in 50% cases and …
ENDOCRINE TUMOURS: Calcitonin in thyroid and extra-thyroid neuroendocrine neoplasms: the two-faced Janus
E Giannetta, V Guarnotta, B Altieri… - European Journal of …, 2020 - academic.oup.com
An increased calcitonin serum level is suggestive of a medullary thyroid cancer (MTC), but is
not pathognomonic. The possibility of false positives or other calcitonin-secreting …
not pathognomonic. The possibility of false positives or other calcitonin-secreting …
Update on multiple endocrine neoplasia type 2: focus on medullary thyroid carcinoma
F Raue, K Frank-Raue - Journal of the Endocrine Society, 2018 - academic.oup.com
Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant hereditary cancer
syndrome caused by missense gain-of-function mutations in the RET proto-oncogene on …
syndrome caused by missense gain-of-function mutations in the RET proto-oncogene on …
Unraveling the complex interplay between transcription factors and signaling molecules in thyroid differentiation and function, from embryos to adults
A López-Márquez, C Carrasco-López… - Frontiers in …, 2021 - frontiersin.org
Thyroid differentiation of progenitor cells occurs during embryonic development and in the
adult thyroid gland, and the molecular bases of these complex and finely regulated …
adult thyroid gland, and the molecular bases of these complex and finely regulated …
On the road again: Establishment and maintenance of stemness in the neural crest from embryo to adulthood
Unique to vertebrates, the neural crest (NC) is an embryonic stem cell population that
contributes to a greatly expanding list of derivatives ranging from neurons and glia of the …
contributes to a greatly expanding list of derivatives ranging from neurons and glia of the …