Although the literature is replete with QSAR models developed for many toxic effects caused
by reversible chemical interactions, the development of QSARs for the toxic effects of …

For toxicological-based structure–activity relationships to advance, will require a better
understanding of molecular reactivity. A rapid and inexpensive spectrophotometric assay for …

Toxicity of chemical compound is a complex phenomenon that may be caused by its
interaction with different targets in the organism. Two distinct types of toxicity can be broadly …

Skin sensitisation potential is an endpoint that needs to be assessed within the framework of
existing and forthcoming legislation. At present, skin sensitisation hazard is normally …

Using abiotic thiol reactivity (EC50) and Tetrahymena pyriformis toxicity (IGC50) data for a
group of halo-substituted ketones, esters and amides (ie SN2 electrophiles) and related …

Assessment of the quality of goodness-of-fit and the confidence in predictivity (prediction
power) are the main terms used to define the statistical quality of QSAR models. Three parts …

Prediction of toxicity of 203 nitro-and cyano-aromatic chemicals to Tetrahymena pyriformis
was carried out by radial basis function neural network, general regression neural network …

We apply a predictive method based on Partial Order Ranking that employs a single
molecular descriptor in the model and that is simple enough to perform calculations by hand …

We designed and synthesized a series of haptens to elicit catalytic antibodies with
phosphatase activity against nerve agents. The design is based on the novel concept of …

This presentation will review the evolution of the workshops from a scientific and personal
perspective. From their modest beginning in 1983, the workshops have developed into …