The pilocarpine animal model of status epilepticus is a well-established, clinically
translatable model that satisfies all of the criteria essential for an animal model of status …

Seizures and other forms of neurovolatility are emerging as druggable prodromal
mechanisms that link traumatic brain injury (TBI) to the progression of later dementias. TBI …

Background Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which
typically develops within 2 years post-injury with poorly understood mechanisms. We …

Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …

Objective To identify postinjury physiologic, behavioral, and cognitive biomarkers for
posttraumatic epilepsy to enrich study populations for long‐term antiepileptogenesis studies …

Objective To characterize neocortical onset status epilepticus (SE) in the C57BL/6J mouse.
Methods We induced SE by administering homocysteine 16‐18 hours after cobalt (Co) …

Noninvasive, affordable circulating biomarkers for difficult-to-diagnose mild traumatic brain
injury (mTBI) are an unmet medical need. Although blood microRNA (miRNA) levels are …

Traumatic brain injury (TBI) is the major and leading cause of mortality and an alarming
public health challenge. TBI leads to permanent cognitive, motor, sensory and psychotic …

Plasma neurofilament light chain (NF-L) levels were assessed as a diagnostic biomarker for
traumatic brain injury (TBI) and as a prognostic biomarker for somatomotor recovery …

Status epilepticus (SE), a condition with abnormally prolonged seizures, is a severe type of
epilepsy. At present, SE is not well controlled by clinical treatments. Antiepileptic drugs …