Adenosine triphosphate binding cassette (ABC) transporters are a broad family of
membrane protein complexes that use energy to transport molecules across cells and/or …

Cardio-oncology encompasses the risk stratification, prognostication, identification and
management of cancer therapeutics related cardiac dysfunction (CTRCD). Cardiovascular …

Doxorubicin (DOXO) remains amongst the most commonly used anti-cancer agents for the
treatment of solid tumors, lymphomas, and leukemias. However, its clinical use is hampered …

There are limited data on the effects of anthracyclines on right ventricular (RV) structure,
function, and tissue characteristics. The goal of this study was to investigate the effects of …

Background Despite the cardiotoxic effect of anthracycline on the left ventricle (LV) was
totally identified. The assessment of the anthracycline effect on the right ventricle (RV) by …

Cardio-oncology guidelines, position statements and clinical trials have focused on the
cardiotoxic effects of cancer therapies upon the left ventricle. 1, 2 However, cancer …

Heart organoid (HO) technology has successfully overcome the limitations of two-
dimensional (2D) disease modeling and drug testing, thereby emerging as a valuable tool in …

Background: Anthracycline (ANT) is the most recognized therapy known to cause
cardiotoxicity, mainly left ventricle (LV) dysfunction. Global Longitudinal Strain (GLS) is the …

Cardiovascular imaging is an evolving component in the care of cancer patients. With
improved survival following prompt cancer treatment, patients are facing increased risks of …

Advances in cancer treatment resulted in augmented patient survival rate. However,
anticancer therapy often causes heart damage in the form of a progressive systolic heart …