Current clinical applications of diffusion-tensor imaging in neurological disorders

WS Tae, BJ Ham, SB Pyun… - Journal of Clinical …, 2018 - synapse.koreamed.org
Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the
structure of white matter. The signal contrast in DTI is generated by differences in the …

Wallerian degeneration beyond the corticospinal tracts: conventional and advanced MRI findings

YJ Chen, SA Nabavizadeh, A Vossough… - Journal of …, 2017 - Wiley Online Library
Wallerian degeneration (WD) is defined as progressive anterograde disintegration of axons
and accompanying demyelination after an injury to the proximal axon or cell body. Since the …

Demyelination precedes axonal loss in the transneuronal spread of human neurodegenerative disease

Y You, C Joseph, C Wang, V Gupta, S Liu, C Yiannikas… - Brain, 2019 - academic.oup.com
The spread of neurodegeneration through the human brain network is reported as
underlying the progression of neurodegenerative disorders. However, the exact …

[HTML][HTML] Structural networks involved in attention and executive functions in multiple sclerosis

S Llufriu, E Martinez-Heras, E Solana, N Sola-Valls… - NeuroImage: Clinical, 2017 - Elsevier
Attention and executive deficits are disabling symptoms in multiple sclerosis (MS) that have
been related to disconnection mechanisms. We aimed to investigate changes in structural …

Mechanisms of central brain atrophy in multiple sclerosis

S Klistorner, MH Barnett… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Change in ventricular volume has been suggested as surrogate measure of
central brain atrophy (CBA) applicable to the everyday management of multiple sclerosis …

Afferent visual pathways in multiple sclerosis: a review

SL Graham, A Klistorner - Clinical & experimental …, 2017 - Wiley Online Library
Multiple sclerosis (MS) is a disease of the central nervous system that involves inflammation
and demyelination at multiple sites and causes a wide variety of clinical presentations with …

Assessment of opicinumab in acute optic neuritis using multifocal visual evoked potential

A Klistorner, Y Chai, L Leocani, P Albrecht, O Aktas… - CNS drugs, 2018 - Springer
Background Multifocal visual evoked potential (MF-VEP) assesses a wider visual field than
full-field VEP (FF-VEP) and potentially offers a more precise analysis of optic nerve injury …

Longitudinal analysis of new multiple sclerosis lesions with magnetization transfer and diffusion tensor imaging

M Gloor, M Andelova, L Gaetano, A Papadopoulou… - European …, 2024 - Springer
Objective The potential of magnetization transfer imaging (MTI) and diffusion tensor imaging
(DTI) for the detection and evolution of new multiple sclerosis (MS) lesions was analyzed …

MS optic neuritis-induced long-term structural changes within the visual pathway

M Pawlitzki, M Horbrügger, K Loewe… - Neurology …, 2020 - AAN Enterprises
Background The visual pathway is commonly involved in multiple sclerosis (MS), even in its
early stages, including clinical episodes of optic neuritis (ON). The long-term structural …

Computational approaches for the reconstruction of optic nerve fibers along the visual pathway from medical images: a comprehensive review

R Jin, Y Cai, S Zhang, T Yang, H Feng… - Frontiers in …, 2023 - frontiersin.org
Optic never fibers in the visual pathway play significant roles in vision formation. Damages of
optic nerve fibers are biomarkers for the diagnosis of various ophthalmological and …