A cold-blooded view of adaptive immunity
MF Flajnik - Nature Reviews Immunology, 2018 - nature.com
The adaptive immune system arose 500 million years ago in ectothermic (cold-blooded)
vertebrates. Classically, the adaptive immune system has been defined by the presence of …
vertebrates. Classically, the adaptive immune system has been defined by the presence of …
[HTML][HTML] Current understanding of natural antibodies and exploring the possibilities of modulation using veterinary models. A review
GIJ Reyneveld, HFJ Savelkoul… - Frontiers in …, 2020 - frontiersin.org
Natural antibodies (NAb) are defined as germline encoded immunoglobulins found in
individuals without (known) prior antigenic experience. NAb bind exogenous (eg, bacterial) …
individuals without (known) prior antigenic experience. NAb bind exogenous (eg, bacterial) …
[HTML][HTML] The genome sequence of Atlantic cod reveals a unique immune system
Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing
commercial fisheries and incipient aquaculture,. Here we present the genome sequence of …
commercial fisheries and incipient aquaculture,. Here we present the genome sequence of …
[HTML][HTML] Immunological control of fish diseases
B Magnadottir - Marine biotechnology, 2010 - Springer
All metazoans possess innate immune defence system whereas parameters of the adaptive
immune system make their first appearance in the gnathostomata, the jawed vertebrates …
immune system make their first appearance in the gnathostomata, the jawed vertebrates …
[HTML][HTML] Adaptive immune responses at mucosal surfaces of teleost fish
JHWM Rombout, G Yang, V Kiron - Fish & Shellfish Immunology, 2014 - Elsevier
This review describes the extant knowledge on the teleostean mucosal adaptive immune
mechanisms, which is relevant for the development of oral or mucosal vaccines. In the last …
mechanisms, which is relevant for the development of oral or mucosal vaccines. In the last …
Immunoglobulins in teleosts
S Bilal, A Etayo, I Hordvik - Immunogenetics, 2021 - Springer
Immunoglobulins are glycoproteins which are produced as membrane-bound receptors on
B-cells or in a secreted form, known as antibodies. In teleosts, three immunoglobulin …
B-cells or in a secreted form, known as antibodies. In teleosts, three immunoglobulin …
[HTML][HTML] Fish lymphocytes: an evolutionary equivalent of mammalian innate-like lymphocytes?
Lymphocytes are the responsible of adaptive responses, as they are classically described,
but evidence shows that subpopulations of mammalian lymphocytes may behave as innate …
but evidence shows that subpopulations of mammalian lymphocytes may behave as innate …
Complement system in zebrafish
S Zhang, P Cui - Developmental & Comparative Immunology, 2014 - Elsevier
Zebrafish is recently emerging as a model species for the study of immunology and human
diseases. Complement system is the humoral backbone of the innate immune defense, and …
diseases. Complement system is the humoral backbone of the innate immune defense, and …
B cells and their role in the teleost gut
Mucosal surfaces are the main route of entry for pathogens in all living organisms. In the
case of teleost fish, mucosal surfaces cover the vast majority of the animal. As these surfaces …
case of teleost fish, mucosal surfaces cover the vast majority of the animal. As these surfaces …
Overview of fish immunity
R Castro, C Tafalla - Mucosal health in aquaculture, 2015 - Elsevier
The purpose of this chapter is to provide readers with a general overview of the fish immune
system, including commonalities and particularities in comparison with higher vertebrate …
system, including commonalities and particularities in comparison with higher vertebrate …