Salmonellae interactions with host processes

DL LaRock, A Chaudhary, SI Miller - Nature Reviews Microbiology, 2015 - nature.com
Salmonellae invasion and intracellular replication within host cells result in a range of
diseases, including gastroenteritis, bacteraemia, enteric fever and focal infections. In recent …

The roles of Peyer's patches and microfold cells in the gut immune system: relevance to autoimmune diseases

N Kobayashi, D Takahashi, S Takano… - Frontiers in …, 2019 - frontiersin.org
Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid
tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport …

[HTML][HTML] Gut-innervating nociceptor neurons regulate Peyer's patch microfold cells and SFB levels to mediate Salmonella host defense

NY Lai, MA Musser, FA Pinho-Ribeiro, P Baral… - Cell, 2020 - cell.com
Gut-innervating nociceptor sensory neurons respond to noxious stimuli by initiating
protective responses including pain and inflammation; however, their role in enteric …

[HTML][HTML] Neonatal gut microbiome and immunity

KZ Sanidad, MY Zeng - Current opinion in microbiology, 2020 - Elsevier
Highlights•In utero microbial stimulation modulates both prenatal and postnatal immune cell
development.•Unique neonatal gut microenvironment allows for progressive colonization of …

[HTML][HTML] Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

NA Mabbott, DS Donaldson, H Ohno, IR Williams… - Mucosal …, 2013 - Elsevier
The transcytosis of antigens across the gut epithelium by microfold cells (M cells) is
important for the induction of efficient immune responses to some mucosal antigens in …

M cells: intelligent engineering of mucosal immune surveillance

A Dillon, DD Lo - Frontiers in immunology, 2019 - frontiersin.org
M cells are specialized intestinal epithelial cells that provide the main machinery for
sampling luminal microbes for mucosal immune surveillance. M cells are usually found in …

Intestinal M cells

H Ohno - The journal of biochemistry, 2016 - academic.oup.com
We have an enormous number of commensal bacteria in our intestine, moreover, the foods
that we ingest and the water we drink is sometimes contaminated with pathogenic …

Modeling host-pathogen interactions in the context of the microenvironment: three-dimensional cell culture comes of age

J Barrila, A Crabbé, J Yang, K Franco… - Infection and …, 2018 - Am Soc Microbiol
Tissues and organs provide the structural and biochemical landscapes upon which
microbial pathogens and commensals function to regulate health and disease. While flat two …

Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella

AE Saliba, L Li, AJ Westermann, S Appenzeller… - Nature …, 2016 - nature.com
Intracellular bacterial pathogens can exhibit large heterogeneity in growth rate inside host
cells, with major consequences for the infection outcome. If and how the host responds to …

Foodborne pathogens and their toxins

T Martinović, U Andjelković, MŠ Gajdošik, D Rešetar… - Journal of …, 2016 - Elsevier
Foodborne pathogens, mostly bacteria and fungi, but also some viruses, prions and
protozoa, contaminate food during production and processing, but also during storage and …