[HTML][HTML] Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

L Chen, Y Zhang, YX Zhang, WL Wang, DM Sun… - Journal of …, 2023 - Elsevier
Tyrosine kinase inhibitors (TKIs) have emerged as the first-line small molecule drugs in
many cancer therapies, exerting their effects by impeding aberrant cell growth and …

A stability indicating method development and validation of a rapid and sensitive RP-HPLC method for Nintedanib and its application in quantification of …

V Velagacherla, Y Nayak, KV Bhaskar… - …, 2023 - f1000research.com
Background: Nintedanib (NTB) is a multiple tyrosine kinase inhibitor, been investigated for
many disease conditions like idiopathic pulmonary fibrosis (IPF), systemic sclerosis …

[PDF][PDF] An UPLC method for the determination of sorafenib in human plasma by fluorimetric detection with pre-column derivatization and application to a …

G Tırıs, ŞE Kepekçi Tekkeli, C Önal… - Revue Roumaine de …, 2022 - revroum.lew.ro
This research presents a new, sensitive and selective UPLC method with fluorometric
detection for the determination of sorafenib in human plasma and application of the method …

[PDF][PDF] DEVELOPMENT OF A RAPID AND SENSITIVE LC-MS/MS ASSAY FOR THE DETERMINATION OF SORAFENIB IN HUMAN PLASMA

D Akiladevi - Methods - afjbs.com
A highly efficient liquid chromatography/tandem mass spectrometric method was devised to
quantify Sorafenib in human plasma with rapidity and sensitivity. The samples underwent …

Analytical estimation methods for determination of sorafenib

T Boovizhikannan, J Kuruba, M Goswami… - World Journal of …, 2022 - wjbphs.com
Sorafenib is an anticancer drug is used to treat late stage kidney and liver cancer. Sorafenib
is used to treat advanced renal cell carcinoma (RCC; a type of cancer that begins in the …