Iron (III) contrast agent candidates for MRI: a survey of the structure–effect relationship in the last 15 years of studies

N Kuźnik, M Wyskocka - European Journal of Inorganic …, 2016 - Wiley Online Library
Iron (III) complexes are under investigation as MRI contrast agents, and new challenges
have delineated the way they are being developed. This review article describes the …

Fe‐HBED analogs: A promising class of iron‐chelate contrast agents for magnetic resonance imaging

BC Bales, B Grimmond, BF Johnson… - Contrast media & …, 2019 - Wiley Online Library
Contrast‐enhanced magnetic resonance imaging is an essential tool for disease diagnosis
and management; all marketed clinical magnetic resonance imaging (MRI) contrast agents …

Mono-, Bi-, and Trinuclear Bis-Hydrated Mn2+ Complexes as Potential MRI Contrast Agents

A Forgacs, M Regueiro-Figueroa, JL Barriada… - Inorganic …, 2015 - ACS Publications
We report a series of ligands containing pentadentate 6, 6′-((methylazanediyl) bis
(methylene)) dipicolinic acid binding units that form mono-(H2dpama), di-(m X (H2dpama) …

A class of water-soluble Fe (III) coordination complexes as T 1-weighted MRI contrast agents

R Wang, L An, J He, M Li, J Jiao, S Yang - Journal of Materials …, 2021 - pubs.rsc.org
Iron-based coordination complexes are showing increasing potential to be alternatives for
T1-weighted magnetic resonance imaging (MRI) and contribute to the safety of gadolinium …

Characterization of the Fe (III)-Tiron System in Solution through an Integrated Approach Combining NMR Relaxometric, Thermodynamic, Kinetic, and Computational …

A Nucera, F Carniato, Z Baranyai… - Inorganic …, 2023 - ACS Publications
The Fe (III)-Tiron system (Tiron= 4, 5-dihydroxy-1, 3-benzenedisulfonate) was investigated
using a combination of 1H and 17O NMR relaxometric studies at variable field and …

Amalgamation of complex iron(III) ions and iron nanoclusters with MWCNTs as a route to potential T2 MRI contrast agents

N Kuźnik, MM Tomczyk, M Wyskocka… - International Journal …, 2015 - Taylor & Francis
Iron-filled multiwall carbon nanotubes (Fe@ MWCNTs) were functionalized toward a variety
of potential magnetic resonance imaging contrast agents. Oxidized Fe@ MWNCTs were …

Alkyl Chain Appended Fe(III) Catecholate Complex as a Dual-Modal T1 MRI–NIR Fluorescence Imaging Agent via Second Sphere Water Interactions

M Duraiyarasu, SS Kumaran… - … Biomaterials Science & …, 2023 - ACS Publications
The C12-alkyl chain-conjugated Fe (III) catecholate complex [Fe (C12CAT) 3] 3–, Fe (C 12
CAT) 3 [C12CAT= N-(3, 4-dihydroxyphenethyl) dodecanamide], was synthesized and …

Transition Metal-based T1 Contrast Agents

R Pujales-Paradela, M Regueiro-Figueroa… - 2017 - books.rsc.org
Transition metal ions such as MnII and FeIII played a key role in the development of MRI.
These metal ions were among the first to be studied as T1-shortening agents by …

Studies on the redox activity of iron N,O-complexes: Potential T1-contrast agents

N Kuźnik, U Chmielniak - Redox Report, 2016 - Taylor & Francis
Objectives: The goal of this study was to determine the redox activity of iron (ethylenebis [2-
(o-hydroxyphenyl) glycine])(EHPG) and (ethylenebis [2-(o-hydroxybenzyl) …

Biotin Conjugated Fe (III)‐Triscatecholate Complex as Tumour Targeting T1 MRI Contrast Agent via Second Sphere Water Relaxation

R Mayilmurugan, M Duraiyarasu… - Chemistry–A European … - Wiley Online Library
The biotin‐conjugated Fe (III) catecholate complex [Fe (BioL) 3] 3‐, Fe (BioL) 3 (BioLH2= N‐
(3, 4‐dihydroxyphenethyl)‐5‐((3aS, 4S, 6aR)‐2‐oxohexahydro‐1H‐thieno [3, 4‐d] imidazol …