miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
Hypoxic tumor-derived exosomal miR-301a mediates M2 macrophage polarization via PTEN/PI3Kγ to promote pancreatic cancer metastasis
X Wang, G Luo, K Zhang, J Cao, C Huang, T Jiang… - Cancer research, 2018 - AACR
Exosomes are emerging as important mediators of the cross-talk between tumor cells and
the microenvironment. However, the mechanisms by which exosomes modulate tumor …
the microenvironment. However, the mechanisms by which exosomes modulate tumor …
MicroRNA let-7 and viral infections: focus on mechanisms of action
A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …
cellular processes, a number of which are involved in host defense mechanisms. In …
MicroRNA epigenetic signatures in human disease
K Piletič, T Kunej - Archives of toxicology, 2016 - Springer
MicroRNAs (miRNAs) are short non-coding RNAs that act as important regulators of gene
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
expression as part of the epigenetic machinery. In addition to posttranscriptional gene …
Cancer-associated fibroblasts-derived exosomes suppress immune cell function in breast cancer via the miR-92/PD-L1 pathway
D Dou, X Ren, M Han, X Xu, X Ge, Y Gu… - Frontiers in …, 2020 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are an essential component in the tumor
microenvironment and have been reported to contribute to tumor progression through many …
microenvironment and have been reported to contribute to tumor progression through many …
Metal–organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics
PH Tong, L Zhu, Y Zang, J Li, XP He… - Chemical …, 2021 - pubs.rsc.org
Biomacromolecular drugs have become an important class of therapeutic agents for the
treatment of human diseases. Considering their high propensity for being degraded in the …
treatment of human diseases. Considering their high propensity for being degraded in the …
MiRNA-210: a current overview
microRNAs (miRNAs) are a group of highly conserved small non-coding RNAs that were
found to enhance mRNA degradation or inhibit post-transcriptional translation. Accumulating …
found to enhance mRNA degradation or inhibit post-transcriptional translation. Accumulating …
Exosomal miRNAs as novel cancer biomarkers: Challenges and opportunities
M Salehi, M Sharifi - Journal of cellular physiology, 2018 - Wiley Online Library
A biomarker with high specificity and sensitivity, is a basic requirement for non‐invasive
cancer diagnosis. Exosomes are a type of lipid bilayer extracellular vesicles (EVs) …
cancer diagnosis. Exosomes are a type of lipid bilayer extracellular vesicles (EVs) …