Purpose Peripheral arterial disease (PAD) is characterized by atherosclerotic arterial
occlusive disease of the lower extremities and is associated with an increased risk of major …

Chronic limb-threatening ischemia (CLTI), the most advanced form of peripheral arterial
disease (PAD), is the comorbidity primarily responsible for major lower-limb amputations …

Chronic limb‐threatening ischemia (CLTI) is associated with significant morbidity, including
major limb amputation, and mortality. Healing ischemic wounds is necessary to optimise …

Precision medicine is a promising framework for generating evidence to improve health and
health care. Yet, a gap persists between the ever-growing number of statistical precision …

Precision medicine is a promising framework for generating evidence to improve health and
health care. Yet, a gap persists between the ever-growing number of statistical precision …

Precision medicine leverages patient heterogeneity to estimate individualized treatment
regimens, formalized, data-driven approaches designed to match patients with optimal …

No consensus or guideline has been established regarding the optimal timing of tissue
resection after revascularization in patients with chronic limb-threatening ischemia (CLTI) …

Wound prevalence is increasing as the global population ages. Older adults are at risk of
wounds from falling and from other medical conditions that contribute to wound development …

Background: Vascular complications from diabetes contribute significantly to major and
minor limb amputations. Diabetes is a major health burden in Saudi Arabia, with increased …

Background: Management of chronic limb-threatening ischemia (CLTI) is based on surgical
or endovascular arterial revas cularization. Over the past two decades, the widespread …