Mechanisms of glomerular injury in immune-complex disease

WG Couser - Kidney international, 1985 - Elsevier
Discussion DR. WILLIAM G. COUSER (Head, Division of Nephrology, and Professor of
Medicine, University of Washington, Seattle, Washington): Several renal lesions have been …

The humoral immune response towards HLA class II determinants in renal transplantation

HE Feucht, G Opelz - Kidney international, 1996 - Elsevier
Once a transplanted organ is exposed to the defense mechanisms of a recipient, its survival
is mainly determined by the strength of the recipient's anti-donor immune response. Despite …

Chronic humoral rejection: identification of antibody-mediated chronic renal allograft rejection by C4d deposits in peritubular capillaries

S Mauiyyedi, P Della Pelle, S Saidman… - Journal of the …, 2001 - journals.lww.com
The pathogenesis of chronic renal allograft rejection (CR) remains obscure. The hypothesis
that a subset of CR is mediated by antidonor antibody was tested by determining whether …

Vascular deposition of complement‐split products in kidney allografts with cell‐mediated rejection

HE Feucht, E Felber, MJ Gokel… - Clinical & …, 1991 - Wiley Online Library
Complement activation in 73 renal transplant biopsies was investigated by indirect
immunoperoxidase staining using MoAbs reactive with complement‐split products. Intense …

Detection of humoral rejection in human cardiac allografts by assessing the capillary deposition of complement fragment C4d in endomyocardial biopsies

TM Behr, HE Feucht, K Richter, C Reiter… - The Journal of Heart and …, 1999 - Elsevier
Background: There are no well-established diagnostic criteria to detect humoral rejection in
organ transplantation. The value of commonly used markers in immunohistochemistry, such …

Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes

P Park, M Haas, PN Cunningham… - American Journal …, 2002 - journals.physiology.org
Ischemia-reperfusion injury (IRI) is a complex and incompletely understood process
involving a cascade of events that culminates in apoptotic and/or necrotic cell death. Natural …

Initial events in the formation of immune deposits in passive Heymann nephritis. gp330-anti-gp330 immune complexes form in epithelial coated pits and rapidly …

D Kerjaschki, A Miettinen, MG Farquhar - The Journal of experimental …, 1987 - rupress.org
The nephritogenic antigen of Heymann's nephritis (HN), gp330, was previously
demonstrated (4-9) to be a resident glycoprotein of coated pits in the glomerular and …

[HTML][HTML] COVID-19–A theory of autoimmunity to ACE-2

P McMillan, BD Uhal - MOJ immunology, 2020 - ncbi.nlm.nih.gov
The COVID-19 (SARS-COV2) pandemic1 represents a significant challenge to the world
from a health and financial perspective. The disease has a high mortality rate and is very …

Specificity, pathogenecity, and clinical value of antiendothelialcell antibodies

C Belizna, JWC Tervaert - Seminars in arthritis and rheumatism, 1997 - Elsevier
OBJECTIVE:: To characterize the putative target antigens for antiendothelial cell antibodies
(AECA), the possible pathophysiological role of AECA, and the clinical value of these …

[PDF][PDF] Lung is the target organ for a monoclonal antibody to angiotensin-converting enzyme

SM Danilov, VR Muzykantov, AV Martynov… - Lab …, 1991 - researchgate.net
" I-labeled mouse monoclonal antibody (MoAb) to human angiotensin-converting enzyme
(ACE), termed 9B9 and cross-reacting with rat and monkey ACE, when injected into the …